Practical teaching of the preparation, isolation, separation and identification of organic compounds based on specific one-step or multi-step syntheses. Acquisition of basic and expanding laboratory techniques used in the synthesis and subsequent isolation of organic substances. 

As part of the first internship, training on organization, familiarization with individual tasks and safety in the organic laboratory is carried out. In the following weeks, students will complete the tasks below: 

1. Laboratory safety training.
2. TLC basic technique for monitoring reaction progress, stationary phase, solvent effect.
3. Dibenzylideneacetone and β-nitrostyrene (condensation of aldehydes and ketones or nitroalkanes).
4. m-Dinitrobenzene (electrophilic aromatic substitution - nitration).
5. Ethyl acetate (Fischer esterification - reaction of carboxylic acid with alcohol).
6. Stilbene (Wittig reaction).
7. Benzoin (benzoin condensation of benzaldehyde catalyzed by thiamine).
8. Benzylidene(phenyl)amine and benzyl(phenyl)amine (reaction of carbonyl compound with amine - preparation of imine and its subsequent reduction to amine).
9. N-(4-Hydroxyphenyl)acetamide (Paracetamol) and N-(4-ethoxyphenyl)acetamide (Phenacetin) (preparation of carboxylic acid amide and Williamson's synthesis of ether).
10. 3-Nitroaniline (partial reduction of dinitro compound).
11. Diphenylmethanol (benzhydrol) (preparation of secondary alcohol by reaction of Grignard reagent with aldehyde).
12. Benzimidazole and benzotriazole (preparation of simple heterocycles).
13. The last week of the semester is reserved for make-ups for missed (due to illness) or unacknowledged (e.g., insufficient knowledge, yields, or failure to follow safety rules) syntheses of the above compounds.

Detailed instructions and readings for each assignment are available in the course elearning course.