Publication detail

Liposomal particles functionalized by antimicrobial ac-tive compoundstive compounds

DZURICKÁ, L. MÁROVÁ, I.

Original Title

Liposomal particles functionalized by antimicrobial ac-tive compoundstive compounds

Type

abstract

Language

English

Original Abstract

Lipid nanoparticles have been developed with the progress innanotechnology and their unique properties have made themone of the most widely used nanoparticles. The presented workis focused on two types of nanostructured particles, liposomesand PHB-liposome particles. Materials were functionalizedby active compounds, thymol and vitamin E. Liposomes wereoverall tested for stability, gradual release of incorporatedsubstances in the model environment and biological activity.Liposomal size and colloid stability were defined by dynamiclight scattering and zeta-potential. Particles they were subject-ed to the characterization of gradual release using the spec-trophotometric method into model environments. Antimi-crobial activity and synergic effect against gram-positive andgram-negative strains of microorganisms were also evaluated.To assess whether prepared nanostructured materials are suit-able for further cosmetic applications, a cytotoxicity assay onthe HaCaT cell line was carried out. Functional liposomal par-ticles showed promising results for various applications as cos-metic preservation and pharmaceutical antimicrobial products.

Keywords

lipid nanoparticles, liposomes, antimicrobial com-pounds, encapsulation

Authors

DZURICKÁ, L.; MÁROVÁ, I.

Released

1. 2. 2023

Publisher

Sciendo

ISBN

2564-615X

Periodical

The EuroBiotech Journal

Year of study

7

Number

1

State

Republic of Italy

Pages from

32

Pages to

74

Pages count

41

URL

https://sciendo.com/article/10.2478/ebtj-2023-0004?fbclid=IwAR2vAcc-FphGdQ7pdyJCVBB48f__sOYw1kQyi64IXmJjs6YDLWfvWJAVI8w

BibTex

@misc{BUT184218,
  author="Lucia {Dzurická} and Ivana {Márová}",
  title="Liposomal particles functionalized by antimicrobial ac-tive compoundstive compounds",
  year="2023",
  journal="The EuroBiotech Journal",
  volume="7",
  number="1",
  pages="32--74",
  publisher="Sciendo",
  issn="2564-615X",
  url="https://sciendo.com/article/10.2478/ebtj-2023-0004?fbclid=IwAR2vAcc-FphGdQ7pdyJCVBB48f__sOYw1kQyi64IXmJjs6YDLWfvWJAVI8w",
  note="abstract"
}