Detail publikace

Liposomal particles functionalized by antimicrobial ac-tive compoundstive compounds

DZURICKÁ, L. MÁROVÁ, I.

Originální název

Liposomal particles functionalized by antimicrobial ac-tive compoundstive compounds

Typ

abstrakt

Jazyk

angličtina

Originální abstrakt

Lipid nanoparticles have been developed with the progress innanotechnology and their unique properties have made themone of the most widely used nanoparticles. The presented workis focused on two types of nanostructured particles, liposomesand PHB-liposome particles. Materials were functionalizedby active compounds, thymol and vitamin E. Liposomes wereoverall tested for stability, gradual release of incorporatedsubstances in the model environment and biological activity.Liposomal size and colloid stability were defined by dynamiclight scattering and zeta-potential. Particles they were subject-ed to the characterization of gradual release using the spec-trophotometric method into model environments. Antimi-crobial activity and synergic effect against gram-positive andgram-negative strains of microorganisms were also evaluated.To assess whether prepared nanostructured materials are suit-able for further cosmetic applications, a cytotoxicity assay onthe HaCaT cell line was carried out. Functional liposomal par-ticles showed promising results for various applications as cos-metic preservation and pharmaceutical antimicrobial products.

Klíčová slova

lipid nanoparticles, liposomes, antimicrobial com-pounds, encapsulation

Autoři

DZURICKÁ, L.; MÁROVÁ, I.

Vydáno

1. 2. 2023

Nakladatel

Sciendo

ISSN

2564-615X

Periodikum

The EuroBiotech Journal

Ročník

7

Číslo

1

Stát

Italská republika

Strany od

32

Strany do

74

Strany počet

41

URL

https://sciendo.com/article/10.2478/ebtj-2023-0004?fbclid=IwAR2vAcc-FphGdQ7pdyJCVBB48f__sOYw1kQyi64IXmJjs6YDLWfvWJAVI8w

BibTex

@misc{BUT184218,
  author="Lucia {Dzurická} and Ivana {Márová}",
  title="Liposomal particles functionalized by antimicrobial ac-tive compoundstive compounds",
  year="2023",
  journal="The EuroBiotech Journal",
  volume="7",
  number="1",
  pages="32--74",
  publisher="Sciendo",
  issn="2564-615X",
  url="https://sciendo.com/article/10.2478/ebtj-2023-0004?fbclid=IwAR2vAcc-FphGdQ7pdyJCVBB48f__sOYw1kQyi64IXmJjs6YDLWfvWJAVI8w",
  note="abstract"
}