Publication detail

Hyaluronic acid gel characterization using classical rheology and passive microrheology technique

HNYLUCHOVÁ, Z. VENEROVÁ, T. PEKAŘ, M.

Original Title

Type

abstract

Language

English

Original Abstract

Passive microrheology is a novel approach determining viscoelastic properties of soft materials based on the Brownian motion of inserted probes. From the particle movement one can calculate viscosity in case of Newtonian fluids and viscoelastic parameters (elastic and storage modulus) in case of non-Newtonian fluids. In our work microrheology was utilized to investigate hyaluronic acid gels formed mixing hyaluronic acid solution with cetyltrimethylammonium bromide (CTAB). Four gels of different concentrations of hyaluronic acid and CTAB were prepared. Their microstructure was characterized via video based particle tracking microrheology using three sizes of inserted particles – 0.1, 0.5, and 1 um to study it s microstructure. All data were compared to classical rheology results providing informations about the sample macrostructure. Each particle size shows different results corresponding to local microenvironment of the particle in response to the mesh size of the polymer structure and doesn t respond to the classical rheology results characterizing macrostructure of the sample.

Keywords

microheology, hyaluronic acid, gel

Authors

HNYLUCHOVÁ, Z.; VENEROVÁ, T.; PEKAŘ, M.

Released

22. 9. 2014

Location

Vienna, Austria

Pages from

Pages to

Pages count

BibTex

@misc{BUT109595,
  author="Zuzana {Hnyluchová} and Tereza {Venerová} and Miloslav {Pekař}",
  title="Hyaluronic acid gel characterization using classical rheology and passive microrheology technique",
  year="2014",
  pages="47--47",
  address="Vienna, Austria",
  note="abstract"
}