Detail publikace

Hyaluronic acid gel characterization using classical rheology and passive microrheology technique

HNYLUCHOVÁ, Z. VENEROVÁ, T. PEKAŘ, M.

Originální název

Typ

abstrakt

Jazyk

angličtina

Originální abstrakt

Passive microrheology is a novel approach determining viscoelastic properties of soft materials based on the Brownian motion of inserted probes. From the particle movement one can calculate viscosity in case of Newtonian fluids and viscoelastic parameters (elastic and storage modulus) in case of non-Newtonian fluids. In our work microrheology was utilized to investigate hyaluronic acid gels formed mixing hyaluronic acid solution with cetyltrimethylammonium bromide (CTAB). Four gels of different concentrations of hyaluronic acid and CTAB were prepared. Their microstructure was characterized via video based particle tracking microrheology using three sizes of inserted particles – 0.1, 0.5, and 1 um to study it s microstructure. All data were compared to classical rheology results providing informations about the sample macrostructure. Each particle size shows different results corresponding to local microenvironment of the particle in response to the mesh size of the polymer structure and doesn t respond to the classical rheology results characterizing macrostructure of the sample.

Klíčová slova

microheology, hyaluronic acid, gel

Autoři

HNYLUCHOVÁ, Z.; VENEROVÁ, T.; PEKAŘ, M.

Vydáno

22. 9. 2014

Místo

Vienna, Austria

Strany od

Strany do

Strany počet

BibTex

@misc{BUT109595,
  author="Zuzana {Hnyluchová} and Tereza {Venerová} and Miloslav {Pekař}",
  title="Hyaluronic acid gel characterization using classical rheology and passive microrheology technique",
  year="2014",
  pages="47--47",
  address="Vienna, Austria",
  note="abstract"
}