Diabetic foot ulcer is an unpleasant chronic wound, that ican no longer be treated by conventional antibiotics due to the antibiotic resistance of the bacteria present. In this project, several nature-derived extracts will be prepared and tested on their antimicrobial and pro-healing properties. Extracts will be stabilized via encapsulation into nanoparticles to improve their stability release. A bioresorbable, and injectable hydrogel based on furcellaran will serve as a carrier for the drug delivery of bioactive nanoparticles.

CEITEC VUT-J-23-8420

Czech

Kadlecová Zuzana, Ing. - principal person responsible
Rychetský Matěj, Ing. - fellow researcher
Vojtová Lucy, doc. Ing., Ph.D. - fellow researcher

Advanced Biomaterials
- responsible department (6.3.2023 - not assigned)
Central European Institute of Technology BUT
- responsible department (31.1.2023 - 6.3.2023)
Advanced Biomaterials
- beneficiary (1.1.2023 - 31.12.2023)

CHAMRADOVÁ, I.; LYSÁKOVÁ, K.; KADLECOVÁ, Z.; VOJTOVÁ, L. Vývoj biokompatibilního “smart” hydrogelu uvolňujícího fibroblastový růstový faktor. III. česko-slovenský kongres "MEZIOBOROVÉ PŘÍSTUPY V HOJENÍ RAN“. Brno: SYMMA, spol. s r.o., 2023. s. 28-28. ISBN: 978-80-11-04155-7.
Detail

RYCHETSKÝ, M.; KADLECOVÁ, Z.; VÍTOVÁ, E.; VOJTOVÁ, L. Maximizing the potential of natural antimicrobial and antioxidant extracts for food application. 3rd Food Chemistry Conference, Dresden; Book of abstracts. Dresden: 2023. p. 168-168.
Detail

KADLECOVÁ, Z.; RYCHETSKÝ, M.; VÍTOVÁ, E.; VOJTOVÁ, L. Preparation of Liposome-enriched system for Controlled Release of Calendula Officinalis Extract in DFU Treatment. THE TWENTY-FOURTH ANNUAL CONFERENCE YUCOMAT 2023 Program and Book of Abstracts Herceg Novi, September 4-8, 2023. 1. Belgrade: Materials Research Society of Serbia, 2023. p. 111-111. ISBN: 978-86-919111-8-8.
Detail

Responsibility: Kadlecová Zuzana, Ing.