Project detail
Stabilization of nature-derived antimicrobial and pro-healing extracts for acute and chronic wound healing
Duration: 01.03.2023 — 28.02.2024
Funding resources
Brno University of Technology - Vnitřní projekty VUT
- whole funder (2023-01-01 - 2024-12-31)
On the project
Diabetic foot ulcer is an unpleasant chronic wound, that ican no longer be treated by conventional antibiotics due to the antibiotic resistance of the bacteria present. In this project, several nature-derived extracts will be prepared and tested on their antimicrobial and pro-healing properties. Extracts will be stabilized via encapsulation into nanoparticles to improve their stability release. A bioresorbable, and injectable hydrogel based on furcellaran will serve as a carrier for the drug delivery of bioactive nanoparticles.
Mark
CEITEC VUT-J-23-8420
Default language
Czech
People responsible
Rychetský Matěj, Ing. - fellow researcher
Vojtová Lucy, doc. Ing., Ph.D. - fellow researcher
Kadlecová Zuzana, Ing. - principal person responsible
Units
Advanced Biomaterials
- beneficiary (2023-01-01 - 2023-12-31)
Central European Institute of Technology BUT
- responsible department (2023-01-31 - 2023-03-06)
Results
KADLECOVÁ, Z.; RYCHETSKÝ, M.; VÍTOVÁ, E.; VOJTOVÁ, L. Preparation of Liposome-enriched system for Controlled Release of Calendula Officinalis Extract in DFU Treatment. THE TWENTY-FOURTH ANNUAL CONFERENCE YUCOMAT 2023 Program and Book of Abstracts Herceg Novi, September 4-8, 2023. 1. Belgrade: Materials Research Society of Serbia, 2023. p. 111-111. ISBN: 978-86-919111-8-8.
Detail
CHAMRADOVÁ, I.; LYSÁKOVÁ, K.; KADLECOVÁ, Z.; VOJTOVÁ, L. Vývoj biokompatibilního “smart” hydrogelu uvolňujícího fibroblastový růstový faktor. III. česko-slovenský kongres "MEZIOBOROVÉ PŘÍSTUPY V HOJENÍ RAN“. Brno: SYMMA, spol. s r.o., 2023. s. 28-28. ISBN: 978-80-11-04155-7.
Detail
RYCHETSKÝ, M.; KADLECOVÁ, Z.; VÍTOVÁ, E.; VOJTOVÁ, L. Maximizing the potential of natural antimicrobial and antioxidant extracts for food application. 3rd Food Chemistry Conference, Dresden; Book of abstracts. Dresden: 2023. p. 168-168.
Detail