Project detail
Understanding of biological function, dynamics and biotechnological consequences of PHA cycle in Rhodospirillum rubrum
Duration: 01.01.2021 — 31.12.2023
Funding resources
Czech Science Foundation - Mezinárodní projekty
- whole funder (2021-03-02 - 2023-12-31)
On the project
Rhodospirillum rubrum is bacterium with great ecological as well as biotechnological importance. This project aims at exploring role of PHA in context of its biological importance under various metabolic situations and conditions with insight into possible biotechnological consequences and applications.
Keywords
polyhydroxyalkanoates; PHA cycle; Rhodospirillum rubrum ; stress robustness
Mark
GF21-15958L
Default language
English
People responsible
Sedlář Karel, doc. Mgr. Ing., Ph.D. - fellow researcher
Obruča Stanislav, prof. Ing., Ph.D. - principal person responsible
Units
Faculty of Chemistry
- responsible department (2020-04-02 - 2020-04-02)
Institute of Food Science and Biotechnology
- beneficiary (2021-01-01 - 2023-12-31)
Department of Biomedical Engineering
- co-beneficiary (2021-01-01 - 2023-12-31)
Results
SLANINOVÁ, E.; RUBANOVÁ, B.; ČERNAYOVÁ, D.; NOVÁČKOVÁ, I.; HAVLÍKOVÁ, M.; MRÁZOVÁ, K.; SEDLÁČEK, P.; OBRUČA, S. Study of aeration and light/dark conditions on production of polyhydroxyalkanoates in bacteria Rhodospirillium rubrum. 2022. p. 1 (1 s.).
Detail
SLANINOVÁ, E.; MRÁZOVÁ, K.; HAVLÍKOVÁ, M.; SEDLÁČEK, P.; ZINN, M.; OBRUČA, S. Rhodospirillum rubrum in the spotlight - use of advanced microscopy techniques for analysis of PHA accumulating microorganisms. ISBP 2022,18th Int´l Symposium on Biopolymers, Sion - Switzerland, 13th-16th September 2022. 1. Švýcarsko: HES-SO Valais-Wallis, 2022. p. 129-129.
Detail
NYKRÝNOVÁ, M.; JUREČKOVÁ, K.; ŠKUTKOVÁ, H.; SLANINOVÁ, E.; OBRUČA, S.; FLEURIOT-BLITMAN, H.; ZINN, M.; SEDLÁŘ, K. Gene expression profiling in Rhodospirillum rubrum. 18th International Symposium on Biopolymers (ISBP). 2022.
Detail
SEDLÁŘ, K.; MUSILOVÁ, J.; ŠKUTKOVÁ, H.; NYKRÝNOVÁ, M.; JUREČKOVÁ, K.; PERNICOVÁ, I.; SLANINOVÁ, E.; FLEURIOT-BLITMAN, H.; ZINN, M.; OBRUČA, S. Improving structural annotation of Rhodospirillum rubrum DSM 467 with RNA-Seq. 18th International Symposium on Biopolymers (ISBP). 2022.
Detail
FLEURIOT-BLITMAN, H.; AMSTUTZ, V.; NYKRÝNOVÁ, M.; SLANINOVÁ, E.; SEDLÁŘ, K.; SEDLÁČEK, P.; OBRUČA, S.; HATZIMANIKATIS, V.; ZINN, M. Increased CO2 gas-liquid mass transfer interferes with Rhodospirillum rubrum’s physiology and production of poly-3-hydroxybutyrate. 18th International Symposium on Biopolymers (ISBP). 2022.
Detail
JUREČKOVÁ, K.; NYKRÝNOVÁ, M.; SLANINOVÁ, E.; BEZDÍČEK, M.; OBRUČA, S.; ŠKUTKOVÁ, H.; SEDLÁŘ, K. Genomic and functional analysis of polyhydroxyalkanoates producer Rhodospirillum rubrum DSM 467. In Proceedings of the 9th International Conference on Chemical Technology. Prague: Czech Society of Industrial Chemistry, 2022. p. 367-372. ISBN: 978-80-88307-11-2.
Detail
JUREČKOVÁ, K.; NYKRÝNOVÁ, M.; SLANINOVÁ, E.; FLEURIOT-BLITMAN, H.; AMSTUTZ, V.; HEŘMÁNKOVÁ, K.; BEZDÍČEK, M.; MRÁZOVÁ, K.; HRUBANOVÁ, K.; ZINN, M.; OBRUČA, S.; SEDLÁŘ, K. Cultivation driven transcriptomic changes in the wild-type and mutant strains of Rhodospirillum rubrum. Computational and Structural Biotechnology Journal, 2024, vol. 23, no. December 2024, p. 2681-2694. ISSN: 2001-0370.
Detail
SLANINOVÁ, E.; JANOŠEC, J.; SEDLÁČEK, P.; OBRUČA, S. In situ study of pigments in metabolically versatile bacterium Rhodospirillum rubrum. Book of abstracts of the 10th International Conference on Chemical Technology. 1. Praha: AMCA,spol. s.r.o., 2023. p. 43-43. ISBN: 978-80-88214-40-3.
Detail
NYKRÝNOVÁ, M.; JUREČKOVÁ, K.; MUSILOVÁ, J.; SLANINOVÁ, E.; OBRUČA, S.; FLEURIOT-BLITMAN, H.; ZINN, M.; SEDLÁŘ, K. Transcriptome Analysis of Rhodospirillum rubrum - Wild Type and Mutant Strains. 11th European Symposium on Biopolymer (ESBP). 2023.
Detail
FLEURIOT-BLITMAN, H.; AMSTUTZ, V.; NYKRÝNOVÁ, M.; SLANINOVÁ, E.; SEDLÁŘ, K.; SEDLÁČEK, P.; OBRUČA, S.; HATZIMANIKATIS, V.; ZINN, M. Investigating the Relationship Between Respiratory Chain Activity and the Electron Sink Mechanism of Poly(3-hydroxybutyrate) (PHB) Accumulation in Rhodospirillum rubrum. 11th European Symposium on Biopolymer (ESBP). 2023.
Detail
JUREČKOVÁ, K.; SLANINOVÁ, E.; OBRUČA, S.; FLEURIOT-BLITMAN, H.; ZINN, M.; SEDLÁŘ, K. Differential expression analysis of RNA-Seq data for identification of housekeeping genes in Rhodospirillum rubrum DSM 467. 11th European Symposium on Biopolymer (ESBP). 2023.
Detail
PACASOVÁ, V.; MRÁZOVÁ, K.; SLANINOVÁ, E.; OBRUČA, S. PHA Metabolism and Stress Response in Bacterium Rhodospirillum rubrum. 2023. p. 119-119.
Detail
SLANINOVÁ, E.; OBRUČA, S.; KOCHERBITOV, V.; SEDLÁČEK, P. On the bioprotective effects of 3-hydroxybutyrate: Thermodynamic study of binary 3HB-water systems. BIOPHYSICAL JOURNAL, 2023, vol. 122, no. 3, p. 460-469. ISSN: 0006-3495.
Detail