Lecture: Designing the interface of nanoparticles operating in biological environments
The Institute of Chemistry of Materials invites you to a lecture by Petr Cígler (CAS), which will take place in lecture room P8 at the Faculty of Chemistry of the Czech Technical University on Monday, 27 February 2023 at 12:00. The lecture will take place in the framework of the seminar "Advanced Materials".
Mgr. Petr Cígler, Ph.D.(Institute of Organic Chemistry and Biochemistry of the CAS, Prague)
Designing the interface of nanoparticles operating in biological environments
The use of nanoparticles in diagnostics, therapeutics and imaging has revolutionized these fields with new properties not available with small molecules. Nanoparticle interfaces provide possibilities for polyvalent and independent attachment of different molecules serving as recognition/targeting structures, optical probes, spin probes or catalysts. However, nanoparticles operating in biological environments require precise control of multiple factors related to surface chemistry. To avoid for example aggregation, off-target interactions, and protein corona formation, appropriate interface design is essential. This talk will present general nanoparticle design strategies and specific examples including nanodiamonds, virus-like particles, and lipid nanoparticles.
Petr Cígler received his PhD from the University of Technology in Prague (2008), then worked as a postdoc at The Scripps Research Institute, La Jolla, USA (2008-2009) in the laboratory of Prof. M. G. Finn. Since 2013 he has been the head of the Synthetic Nanochemistry research group at the Institute of Organic Chemistry and Biochemistry of the CAS in Prague. His research interests include surface chemistry of nanoparticles, their biointerfaces and applications in biomedicine and sensors. He develops surface chemistry of diamond and develops new types of quantum nanosensors. He has published more than 100 peer-reviewed papers, H-index 33.
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Link | https://www.fch.vut.cz/en/faculty/organizational-structure/ims/news/f142507/d256810 |