Course detail
Biochemistry I
FCH-BC_BCH1Acad. year: 2025/2026
Not applicable.
Language of instruction
Number of ECTS credits
Mode of study
Guarantor
Entry knowledge
Rules for evaluation and completion of the course
Aims
Study aids
Prerequisites and corequisites
Basic literature
Vodrážka Z. : Biochemie. Academia, Praha 1996. (CS)
Recommended reading
Classification of course in study plans
- Programme BPCP_CHTN Bachelor's 2 year of study, summer semester, compulsory
- Programme BPCP_CHMA Bachelor's 2 year of study, summer semester, compulsory
- Programme BKCP_AAEFCH Bachelor's 2 year of study, summer semester, compulsory
- Programme BKCP_CHTM Bachelor's 2 year of study, summer semester, compulsory-optional
- Programme BKCP_CHTP Bachelor's
specialization CHPL , 2 year of study, summer semester, compulsory
specialization PCH , 2 year of study, summer semester, compulsory
specialization BT , 2 year of study, summer semester, compulsory - Programme BKCP_CHTPO Bachelor's
specialization PCH , 2 year of study, summer semester, compulsory
specialization BT , 2 year of study, summer semester, compulsory
specialization CHPL , 2 year of study, summer semester, compulsory - Programme BPCP_AAEFCH Bachelor's 2 year of study, summer semester, compulsory
- Programme BPCP_CHTM Bachelor's 2 year of study, summer semester, compulsory-optional
- Programme BPCP_CHTP Bachelor's
specialization CHPL , 2 year of study, summer semester, compulsory
specialization PCH , 2 year of study, summer semester, compulsory
specialization BT , 2 year of study, summer semester, compulsory - Programme BPCP_CHTPO Bachelor's
specialization CHPL , 2 year of study, summer semester, compulsory
specialization PCH , 2 year of study, summer semester, compulsory
specialization BT , 2 year of study, summer semester, compulsory - Programme BPCP_CHCHTE Bachelor's 2 year of study, summer semester, compulsory
- Programme BKCP_CHCHTE Bachelor's 2 year of study, summer semester, compulsory
- Programme NPCP_CHTM Master's 1 year of study, summer semester, elective
2 year of study, summer semester, elective - Programme NKCP_CHTM Master's 1 year of study, summer semester, elective
2 year of study, summer semester, elective
Type of course unit
Lecture
Teacher / Lecturer
Syllabus
1. Látkové složení živé hmoty. Struktura buňky. Organizace biologických systémů.
2. Aminokyseliny. Peptidická vazba. Bílkoviny - struktura a stabilita, denaturace.
3. Metody izolace, purifikace a charakterizace biopolymerů .
4. Metody ke zjišťování struktury biomolekul a jejich změn.
5. Sacharidy - monosacharidy, oligosacharidy, polysacharidy, složené sacharidy.
6. Lipidy - struktura a klasifikace. Jednoduché a složené lipidy. Izoprenoidy.
7. Biomembrány - struktura a funkce. Membránový transport.
8. Enzymy a biokatalýza. Substrátová specifita. Koenzymy. Regulace enzymové aktivity. Stručné názvosloví enzymů.
9. Enzymová kinetika. Rovnice Michaelise a Mentenové. Inhibice. Analýza kinetických dat. Reakce se dvěma substráty.
10. Bioenergetika, makroergické sloučeniny, metabolismus základních typů živin - centrální dráhy.
11. Metaboplismus sacharidů, lipidů, aminokyselin.
12. Biologické oxidace, - dýchací řetězec, fotosyntéza. Energetické spřažení.
13. Nukleové kyseliny - typy, struktura DNA a RNA. Funkce v organismu, genetický kód. Replikace, transkripce, translace