Course detail
Biochemistry I
FCH-BA_BCH1Acad. year: 2024/2025
Organization and composition of living cells and cellular compartments. Amino acids - composition and structure, peptides, proteins. Methods of isolation and separation of proteins. Functional roles of proteins. Nucleic acids. Carbohydrates. Lipids. Biomembranes. Metabolic pathways. termodynamic relationships and energy-rich components. Enzymology, enzyme catalysis. Enzyme kinetics, inhibition of enzymes. Regulation of enzyme activity. Nucleic acids. Applied biochemistry.
Language of instruction
Number of ECTS credits
Mode of study
Guarantor
Offered to foreign students
Entry knowledge
Rules for evaluation and completion of the course
none
Aims
After passing of the course Biochemistry I is student mastered of overview about cell composition, structure, properties and function of basic groups of biomolecules, e.g. amino acids, proteins, saccharides, lipids and nucleic acids. Further, basic knowledge about structure of biomemrbanes and types of membrane transport are introduced and basic principles of enzyme catalysis, kinetics and regulation of enzyme activity are elucidated. Next, overview about methods of isolation and characterization of biopolymers will be obtained and some applications including enzyme engineering and genetic engineering will be discussed.
Study aids
Prerequisites and corequisites
Basic literature
Recommended literature
Alberts et al: Molecular Biology of the Cell. Garland Science, 2003. (EN)
Classification of course in study plans
- Programme BPCP_CHTPO Bachelor's
specialization CHPL , 2 year of study, summer semester, compulsory
specialization PCH , 2 year of study, summer semester, compulsory
specialization BT , 2 year of study, summer semester, compulsory - Programme BKCP_CHTPO Bachelor's
specialization PCH , 2 year of study, summer semester, compulsory
specialization BT , 2 year of study, summer semester, compulsory
specialization CHPL , 2 year of study, summer semester, compulsory - Programme BKCP_AAEFCH Bachelor's 2 year of study, summer semester, compulsory
- Programme BKCP_CHCHTE Bachelor's 2 year of study, summer semester, compulsory
- Programme BKCP_CHTM Bachelor's 2 year of study, summer semester, compulsory-optional
- Programme BPCP_AAEFCH Bachelor's 2 year of study, summer semester, compulsory
- Programme BPCP_CHCHTE Bachelor's 2 year of study, summer semester, compulsory
- Programme BPCP_CHMA Bachelor's 2 year of study, summer semester, compulsory
- Programme BPCP_CHTM Bachelor's 2 year of study, summer semester, compulsory-optional
- Programme BPCP_CHTP Bachelor's
specialization CHPL , 2 year of study, summer semester, compulsory
specialization PCH , 2 year of study, summer semester, compulsory
specialization BT , 2 year of study, summer semester, compulsory - Programme BKCP_CHTP Bachelor's
specialization CHPL , 2 year of study, summer semester, compulsory
specialization PCH , 2 year of study, summer semester, compulsory
specialization BT , 2 year of study, summer semester, compulsory - Programme NPAP_ENVI Master's 1 year of study, summer semester, compulsory
- Programme BPCP_MPMU Bachelor's 2 year of study, summer semester, compulsory
Type of course unit
Lecture
Teacher / Lecturer
Syllabus
Amino acids - composition and structure, peptides, proteins.
Methods of isolation, purification and separation of proteins.
Functional roles of proteins.
Carbohydrates - monosaccharides, polysaccharides, glycoproteins.
Lipids - structure and classification. Triglycerides, phospholipids. Isoprenoids.
Biomembranes. Membrane transport.
Enzymology, enzyme catalysis. Substrate specificity. Cofactors. Regulation of enzyme activity.
Enzyme kinetics, Michaelis-Menten equation. Inhibition of enzymes.
Metabolic pathways. termodynamic relationships and energy-rich components.
Nucleic acids - structure and function. DNA, RNA.
Applide biochemistry - modern biotechnology, genetic engineering.