Course detail

Organic Chemistry II

FCH-BAT_OCH2Acad. year: 2023/2024

Halogen deivatives, nucleophilic substitution at saturated carbon atom, eleimination reactions. Alcohols phenols, polyhydroxyderivatives. Oxidation alcohols and phenols. Ethers, peroxides, epoxides, crown-ethers. Thiols, sulfides, sulfonic acids and their derivatives. Esters of inorganic acids. Amines, diazotation, arendiazonium salts and application, amine oxides. Diazo compounds, carbenes.Azides. Nitrocompounds. Organometallic compounds. Aldehydes and ketones, nucleophilic addition to the carbonyl group, aldolization reactions of aldehydes and ketones. Saccharides, structure and reactivity.Carboxylic acids, esterification, acyl halogenides, anhydrides, esters, amides. Halogen and amino acids, peptides, carbonic acid derivatives. Dicarbonyl compounds, unsaturated carbonyl compounds, quinones. Heterocyclic compounds.

Language of instruction

English

Number of ECTS credits

Mode of study

Not applicable.

Guarantor

prof. Ing. Jozef Krajčovič, Ph.D.

Department

Institute of Chemistry and Technology of Environmental Protection (ÚCHTOŽP)

Offered to foreign students

Of all faculties

Entry knowledge

Knowledge of the Organic Chemistry I and examination from the course contents.

Rules for evaluation and completion of the course

Completing the tutorial of Organic Chemistry, which is accompanying the lectures, requires passing 12 written tests. Those, who successfully pass at least 7 tests during the semester with more than 60%, may get credit automatically. Alternatively, students are obliged to pass another test at the end of term with gain at least 60%.
The examination consists from written test and oral examination. In the written part knowledge from Organic Chemistry II is tested, in oral exam then knowledge from the whole Organic chemistry.

Completing the tutorial of Organic chemistry requires the attendance and successfully passed all class exams. The examination consists from written test and oral examination.

Aims

The aim of the course is acquiring deeper knowledge of organic compounds reactivity. The course is connected with the previous course Organic Chemistry I, which represents necessary prerequisite for understanding the subject matter of this course. The aim of the course is understanding the structure and reactivity of various functional groups bound at various carbon skeletons, influence of the skeleton upon reactivity of the group and the opposite influence of the group upon reactivity of skeleton.
Completing the course of Organic Chemistry II in connection with course Organic Chemistry I, students acquire the complex knowledge of structure, reactivity and stereochemistry of hydrocarbon derivatives and heterocyclic compounds. The knowledge acquired enables to work both in research and practice of organic chemistry, in control laboratories and state administration authorities.

Study aids

Not applicable.

Prerequisites and corequisites

Not applicable.

Basic literature

Solomons T.W.G., Fryhle C.B.: Organic Chemistry. 9th Ed.,Wiley 2008. (EN)

Type of course unit

Lecture

26 hod., optionally

Teacher / Lecturer

prof. Ing. Jozef Krajčovič, Ph.D.

Syllabus

The course provides knowledge of basic organic chemistry in terms of mechanisms of organic reactions, basic physicochemical properties of selected types of organic compounds and the student learns the basic pillars of organic chemistry and organic synthesis. The course is divided into several chapters:

1. Halogenated derivatives of organic compounds, nucleophilic substitution on a saturated carbon atom, and elimination reactions.
2.-3. Alcohols, phenols, polyhydroxy compounds and their reactions.
4. Ethers, peroxides, epoxides. Thiols, sulphides, sulfonic acids and their derivatives.
5.-6. Amines, their diazotation, formation of arendiazonium salts and their uses. Diazocompounds. Azides. Nitro compounds.
7. Organometallic compounds and their reactions.
8.-10. Carbonyl compounds - aldehydes and ketones, nucleophilic addition to the C=O group, aldolysis reactions of aldehydes and ketones.
11.-13. Carboxylic acids and their functional derivatives: acyl halides, anhydrides, esters, amides.

Exercise

39 hod., compulsory

Teacher / Lecturer

prof. Ing. Jozef Krajčovič, Ph.D.

Syllabus

Teaching takes place according to the lecture syllabus of the course.

Elearning

eLearning: currently opened course