Czech

Not applicable.

Basic knowledge of both Powder Technology theory and practice used in today´s pharmaceutical processes.

Chemical engineering I and II

Not applicable.

The course uses teaching methods in form of individual consultation. The e-learning system (LMS Moodle) is available to teachers and students.

Examination in the oral form, knowledge in the given lectures extent is demanded.

1. Characterization of the particular systems , the basic parameters of the particular systems and their measurement. Grain size and morphology of the particle constituents of particulate systems.
2. Transportation, convaing and handling with particular systems. The issue of classification and separation .
3. The processes of disintegration, preparation of ultra-fine to nano - fine particulate systems.
4. Homogenization of powder systems, segregation, compaction, agglomeration, granulation, tabletting.
5. Drying and heat exposure of ultrafine particulate matter. Lyophilization .
6. Bulk properties of particulate systems, ways of the bulk properties measurement. Basis of bulk storage, hoppers, feeders and warehousing design.
7. Surface properties of fine-grained particulate matter , sorption properties , moisture transport and equilibrium moisture content of particulate matter.
8. Surface modification of powders. Surface treatment of solid dosage forms. Making the multi-layers systems.
9. Making suspensions and dispersions. Homogenization of liquids and pastes .
10. Sampling of particulate systems. Performance of solid dosage forms in containers , " blistering ", expedition .
11. The issue of transport, storage and dosing of liquid systems.
12. Specifics of measurement and control of chemical- pharmaceutical processes. The issue of planning , approval and implementation of new pharmaceutical processes.
13. Aspects of dust. Work safety with particular biological and chemical- active systems.

Not applicable.

General knowledge of students about the today´s Powder Technology science possibilities used in practice of pharmaceuticals production.

Lectures on the most problematical points of the Powder Technology processes in the pharmaceutical industry. Permanently inovated lectures demand attending of students. Recommended literature and the main thesis of the lectures on www pages of Faculty of Chemistry is insufficient for the successfull exam.

Not applicable.

Not applicable.

Hanika J.: Farmaceutické inženýrství. VSCHT Praha, 2013. (CS)
Hovorka F.: Technologie chemických výrob. VŠCHT Praha, 2012. (CS)

M. J. Rhodes: Principles of Powder Technology, John Wiley and sons, LTD, 1990 (EN)
Masuda H., Higashitani K, Yoshida H.: Powder Technology Handbook, Third Edition, CRC Press, 2006. ISBN: 978-1574447828 H. Masuda, K. Higashitani, H. Yoshida, Taylor and Francis, 2006, ISBN-13: 978-1574447828
Salman A.D., Ghadiri M., Hounslow M.J.: Handbook of Powder Technology, Volume 12, Elsevier, 2007. ISBN 978-0444530806