Course detail

Molecular Genetics I

FCH-BC_MOG1Acad. year: 2022/2023

History of molecular genetics. Genetic information and the genetic code. Molecular structure of procaryotic and eucaryotic genome. Replication and transcription of procaryotic and eucaryotic genome. Postranscriptional modification and processing of RNA. Translation and posttranslational processing. Regulation of gene expression. Molecular basis of cancerogenesis (oncogenes, antioncogenes). Molecular mechanisms of mutagenesis and recombination. Mobile elements. Repair mechanisms of damaged DNA. Basic methods of molecular genetics. DNA cloning. Gene engineering and transgenic organisms.

Language of instruction

Czech

Number of ECTS credits

Mode of study

Not applicable.

Guarantor

Mgr. Jan Smetana, Ph.D.

Department

Institute of Food Science and Biotechnology (ÚCHPBT)

Learning outcomes of the course unit

The basic knowledge of molecular biology, using methods of molecular biology and gene engineering in the research area, in industry, agriculture and medicine.

Prerequisites

The structure and basic functions of living systems, their reproduction, cell chemistry, structure and function of biomacromolecules.

Co-requisites

Not applicable.

Planned learning activities and teaching methods

The course uses teaching methods in form of Lecture - 2 teaching hours per week. The e-learning system (LMS Moodle) is available to teachers and students.

Assesment methods and criteria linked to learning outcomes

Oral exam

Course curriculum

Work placements

Not applicable.

Aims

This lecture is conceived as an introduction into molecular biology and genetics and gives the explanation of processes on molecular level in relation to the basic functions of living systems. The second part of the lecture is focused on basic methods of molecular genetics and their applications in gene engineering which is a main tool of modern biotechnologies.

Specification of controlled education, way of implementation and compensation for absences

Lectures are optional, no control tests during the semester.

Recommended optional programme components

Not applicable.

Prerequisites and corequisites

Not applicable.

Basic literature

Rosypal S. a kol.: Úvod do molekulární biologie. S. Rosypal, Brno 2006. (CS)
Sundstad P., Simmons M.J. Genetika. Český překlad, Masarykova univerzita, Brno 2009 (CS)

Type of course unit

Lecture

26 hod., optionally

Teacher / Lecturer

Mgr. Jan Smetana, Ph.D.

Elearning

eLearning: currently opened course