Publication detail

Novel conductive PEDOT:DBSA hydrogels with tuneable properties for bioelectronics

MALEČKOVÁ, R. TUMOVÁ, Š. SMÍSITEL, P. SMILEK, J. ŠIMŮNKOVÁ, H. PEŠKOVÁ, M. KUBÁČ, L. HUBÁLEK, J. VÍTEČEK, J. VALA, M. WEITER, M.

Original Title

Novel conductive PEDOT:DBSA hydrogels with tuneable properties for bioelectronics

Type

journal article in Web of Science

Language

English

Original Abstract

Conductive hydrogels represent a promising class of novel materials to interface the human body with electronics; however, there is still a high demand for hydrogels that would truly meet the conductivity requirements for efficient signal transmission between the tissues and the device. To address this demand, herein we report the preparation of a novel pure conductive hydrogel based on PEDOT:DBSA at room temperature; thus, we offer an efficient alternative to the commonly used PEDOT:PSS, whose biocompatibility was proven to be limited. With thorough characterization, this work also contributes towards a better understanding of the relationship between the hydrogel structure and electrical properties. The mechanical strength of the novel hydrogel network is tuneable and can be easily tailored to the needs of a given application. Together with an exceptionally low value of Young's modulus, this material provides mechanical properties matching those of soft tissues. Biocompatibility tests confirmed excellent compatibility with murine endothelial cells. The total conductivity of the hydrogel is sufficient for cell-targeted bioelectronic applications, such as cell stimulation; moreover, low impedance was determined at 1 Hz, suggesting that the PEDOT:DBSA hydrogel might offer a truly functional interface between a biological tissue and an electronic device.

Keywords

PEDOT, conductive hydrogels, soft bioelectronics , impedance spectroscopy, mechanical properties

Authors

MALEČKOVÁ, R.; TUMOVÁ, Š.; SMÍSITEL, P.; SMILEK, J.; ŠIMŮNKOVÁ, H.; PEŠKOVÁ, M.; KUBÁČ, L.; HUBÁLEK, J.; VÍTEČEK, J.; VALA, M.; WEITER, M.

Released

22. 2. 2025

Publisher

ROYAL SOC CHEMISTRY

Location

CAMBRIDGE

ISBN

2633-5409

Periodical

Materials Advances

Year of study

6

Number

4

State

United Kingdom of Great Britain and Northern Ireland

Pages from

1278

Pages to

1287

Pages count

10

URL

https://pubs.rsc.org/en/content/articlelanding/2025/ma/d4ma00987h

BibTex

@article{BUT197075,
  author="Romana {Malečková} and Šárka {Tumová} and Petr {Smísitel} and Jiří {Smilek} and Helena {Šimůnková} and Michaela {Pešková} and Lubomír {Kubáč} and Jaromír {Hubálek} and Jan {Víteček} and Martin {Vala} and Martin {Weiter}",
  title="Novel conductive PEDOT:DBSA hydrogels with tuneable properties for bioelectronics",
  journal="Materials Advances",
  year="2025",
  volume="6",
  number="4",
  pages="1278--1287",
  doi="10.1039/d4ma00987h",
  issn="2633-5409",
  url="https://pubs.rsc.org/en/content/articlelanding/2025/ma/d4ma00987h"
}