Publication detail
Natural polysaccharide Gum Karaya as novel biomaterial in regenerative medicine
POŠTULKOVÁ, H. VOJTOVÁ, L. JANČÁŘ, J.
Original Title
Natural polysaccharide Gum Karaya as novel biomaterial in regenerative medicine
Type
abstract
Language
English
Original Abstract
Natural polysaccharides are biodegradable, freely available, relatively cheap and nontoxic materials with great potential in medical applications. The polysaccharide hydrogels supports wound healing by providing moist environment and can be utilized as wound dressing for soft tissue regeneration (e.g. skin burns or ulcers). One suitable candidate is Gum Karaya (GK), anionic polysaccharide containing β-D-galactose, L-rhamnose, β-D-glucuronic acid and D-galacturonic acid. Natural GK is partially acetylated high molecular weight polymer (Mw ≈ 9 mil Da), water insoluble, having high swelling and retention capacity, high viscosity and inherent antimicrobial activity. [1, 2, 3] The objective of this study is to prepare a soluble sample of GK by alkali treatment followed by designing new procedure for GK hydrogel preparation which meets requirements for use as wound healing coverings. Prepared samples were characterized by SEM, FTIR, NMR, TGA, DSC and rheology.
Keywords
natural gum, polysaccharide, gum karaya, chemical modification, characterization, solubility
Authors
POŠTULKOVÁ, H.; VOJTOVÁ, L.; JANČÁŘ, J.
Released
2. 9. 2015
Publisher
CEITEC
Location
Brno
Pages from
132
Pages to
132
Pages count
1
URL
BibTex
@misc{BUT115916,
author="Hana {Poštulková} and Lucy {Vojtová} and Josef {Jančář}",
title="Natural polysaccharide Gum Karaya as novel biomaterial in regenerative medicine",
year="2015",
pages="132--132",
publisher="CEITEC",
address="Brno",
doi="10.1371/journal.pone.0100028",
url="http://www.ceitec.eu/creating-life-in-3d/poster-session/",
note="abstract"
}