Publication detail

Influence of Nanograin Size ZrO2 and Al2O3 Ceramics on Biological Response of Cells

MATOUŠEK, A. KUKLETOVÁ, M. CIHLÁŘ, J.

Original Title

Type

journal article - other

Language

English

Original Abstract

The influence of the grain size of alumina and zirconia ceramics on the spreading and adhesion of MG63 cell lines was investigated. Single-component ceramics and layered composite ceramics were prepared by electrophoretic deposition, uniaxial pressing and sintering. The grain size of zirconia was 100 nm to 2.7 mikro m and that of alumina was 0.5 mikro m to 1.5 mikro m. Subsequently, sample surfaces were polished and thermally etched. Biological tests of adhesion (0.5 to 8 h) were used to evaluate the influence of grain size on biological response. The highest cell spreading was obtained for ZrO2 ceramics with an average grain size of 100 and 120 nm. The cell selection was observed on layered ZrO2/Al2O3 composites. The cells predominantly adhered to ZrO2 layers. The results showed a positive influence of nanostructured ceramic surfaces on biological behaviour of MG63 cells

Keywords

Alumina, zirconia, bioactivity, cell adhesion, cell proliferation, osteoblast cell, surface roughness

Authors

MATOUŠEK, A.; KUKLETOVÁ, M.; CIHLÁŘ, J.

RIV year

2013

Released

1. 11. 2013

Publisher

Trans Tech Publications Ltd

Location

Durnten-Zurich, Switzerland

ISBN

1013-9826

Periodical

Key Engineering Materials (print)

Year of study

587

Number

State

Swiss Confederation

Pages from

132

Pages to

137

Pages count

BibTex

@article{BUT103005,
  author="Aleš {Matoušek} and Martina {Kukletová} and Jaroslav {Cihlář}",
  title="Influence of Nanograin Size ZrO2 and Al2O3 Ceramics on Biological Response of Cells",
  journal="Key Engineering Materials (print)",
  year="2013",
  volume="587",
  number="25",
  pages="132--137",
  issn="1013-9826"
}