Publication detail
Whey: Attractive Substrate for Microbial Production of Substances and Materials for Medical Applications
OBRUČA, S. MÁROVÁ, I. ČERTÍK, M.
Original Title
Whey: Attractive Substrate for Microbial Production of Substances and Materials for Medical Applications
Type
book chapter
Language
English
Original Abstract
Whey is an important surplus product of food industry. Based on the point of view, huge quantities of whey produced worldwide can represent an environmental problem with its disposal, or, due to the fact that whey is rich in fermentable nutrients, it can be considered as an attractive substrate for microbial production of various industrially interesting products. Therefore; this chapter is intended to summarize possible up-stream processing methods, general principles and fermentation strategies for the microbial productions using whey as a substrate. Further; among huge amount of potential products, this review focuses on the production of high value substances and materials which find applications especially in the field of health care and medicine. At first, many biologically active substances such as vitamins, carotenoids, antibiotics etc. can be produced from whey employing various microorganisms (bacteria, yeasts as well as fungi) and cultivation strategies. Moreover, also number of biopolymers which can be used in form of drug carriers, scaffolds, sutures, adhesives etc. can be produced by using whey as a cheap complex substrate. Apart from poly(lactic acid), these materials include bacterial polyesters- polyhydroxyalkanoates and also several polysaccharides such as xanthan, alginate, hyaluronic acid, gellan, pullulan, dextran or chitosan. In addition, the aim of this review is also to provide basic economical consideration of fermentation processes. In conclusion; utilization of whey as a substrate for microbial productions of high value products could result in a very promising process meeting both economic and ecological requirements.
Keywords
whey, fermentation, up-stream, down-stream, carotenoids, antibiotics, lactic acid, xanthan, dextran, pullulan, alginate, chitosan, hyaluronic acid, gellan, polyhydroxyalkanoates
Authors
OBRUČA, S.; MÁROVÁ, I.; ČERTÍK, M.
RIV year
2012
Released
1. 8. 2012
Publisher
Nova Publishers
Location
New York
ISBN
978-1-61942-862-1
Book
Whey: Types, Composition and Health Implications
Edition
1
Edition number
1
Pages from
53
Pages to
92
Pages count
40
BibTex
@inbook{BUT93416,
author="OBRUČA, S. and MÁROVÁ, I. and ČERTÍK, M.",
title="Whey: Attractive Substrate for Microbial Production of Substances and Materials for Medical Applications",
booktitle="Whey: Types, Composition and Health Implications",
year="2012",
publisher="Nova Publishers",
address="New York",
series="1",
edition="1",
pages="53--92",
isbn="978-1-61942-862-1"
}