Strategies for Enhancing Poly(3-hydroxybutyrate) Production in Selected Bacterial Strains

journal article - other

English

Polyhydroxyalkanoates (PHAs) are a group of bacterial polyesters that have received much interest in recent times due to their biodegradable nature and mechanical properties which are very similar to traditional plastics from petrochemical routes. The most common PHA is poly(3-hydroxybutyrate) (PHB). Many bacterial strains use PHB as carbon and reducing power storage material. Bacterial strains usually accumulate PHB during exposition to stress condition. Typical strategy, which is widely used for enhancing of production, is limitation with nitrogen, phosphor or another element when excess amount of carbon source is present. The influences of selected stress factors on accumulation of PHB were tested in this work. Limitations with nitrogen and/or phosphor source were tested during growth of bacteria on synthetic as well as natural waste carbon source. Oxygen limitation was studied too. Finally, peroxide stress, osmotic stress, ethanol stress and UV radiation were studied as additional stress factors to nutrition starvation. Combined effect of exogenous stress could lead to increased accumulation of PHB in selected bacterial strains.

poly(3-hydroxybutyrate), stress condition

OBRUČA, S.; MELUŠOVÁ, S.; MÁROVÁ, I.; SVOBODA, Z.

2008

9. 9. 2008

CSCH

Brno

1213-7103

Chemické listy

102

15

Czech Republic

1255

1256

2