Publication detail

Genomic and Phenotypic Comparison of Polyhydroxyalkanoates Producing Strains of genus Caldimonas/Schlegelella

MUSILOVÁ, J. KOUŘILOVÁ, X. HEŘMÁNKOVÁ, K. BEZDÍČEK, M. IEREMENKO, A. DVOŘÁK, P. OBRUČA, S. SEDLÁŘ, K.

Original Title

Genomic and Phenotypic Comparison of Polyhydroxyalkanoates Producing Strains of genus Caldimonas/Schlegelella

Type

journal article in Web of Science

Language

English

Original Abstract

Polyhydroxyalkanoates (PHAs) have emerged as an environmentally friendly alternative to conventional polyesters. In this study, we present a comprehensive analysis of the genomic and phenotypic characteristics of three non-model thermophilic bacteria known for their ability to produce PHAs: Schlegelella aquatica LMG 23380T, Caldimonas thermodepolymerans DSM 15264, and C. thermodepolymerans LMG 21645 and the results were compared with the type strain C. thermodepolymerans DSM 15344T. We have assembled the first complete genomes of these three bacteria and performed the structural and functional annotation. This analysis has provided valuable insights into the biosynthesis of PHAs and has allowed us to propose a comprehensive scheme of carbohydrate metabolism in the studied bacteria. Through phylogenomic analysis, we have confirmed the synonymity between Caldimonas and Schlegelella genera, and further demonstrated that S. aquatica and S. koreensis, currently classified as orphan species, belong to the Caldimonas genus.

Keywords

Caldimonas; Schlegelella; de novo assembly; PHAs; Next-Generation Industrial Biotechnology; LMG 23380T; DSM 15264; LMG 21645; DSM 15344T

Authors

MUSILOVÁ, J.; KOUŘILOVÁ, X.; HEŘMÁNKOVÁ, K.; BEZDÍČEK, M.; IEREMENKO, A.; DVOŘÁK, P.; OBRUČA, S.; SEDLÁŘ, K.

Released

30. 10. 2023

Publisher

Elsevier

ISBN

2001-0370

Periodical

Computational and Structural Biotechnology Journal

Year of study

21

Number

November

State

Kingdom of Sweden

Pages from

5372

Pages to

5381

Pages count

10

URL

https://www.sciencedirect.com/science/article/pii/S2001037023004075

Full text in the Digital Library

http://hdl.handle.net/11012/244318

BibTex

@article{BUT185013,
  author="Jana {Musilová} and Xenie {Kouřilová} and Kristýna {Heřmánková} and Matěj {Bezdíček} and Anastasiia {Ieremenko} and Pavel {Dvořák} and Stanislav {Obruča} and Karel {Sedlář}",
  title="Genomic and Phenotypic Comparison of Polyhydroxyalkanoates Producing Strains of genus Caldimonas/Schlegelella",
  journal="Computational and Structural Biotechnology Journal",
  year="2023",
  volume="21",
  number="November",
  pages="5372--5381",
  doi="10.1016/j.csbj.2023.10.051",
  issn="2001-0370",
  url="https://www.sciencedirect.com/science/article/pii/S2001037023004075"
}