Publication detail

LA-ICP-MS in medical research

MACHALOVÁ, M. VAŠINOVÁ GALIOVÁ, M. STRAČINA, T.

Original Title

Type

abstract

Language

English

Original Abstract

This study aims to analyse the distribution of elements in rat hearts with artificially induced myocardial fibrosis. Within this study, an appropriate LA-ICP-MS methodology has been developed to identify the changes in elemental distribution as a result of myocardial fibrosis via comparison healthy and fibrotic tissue and to locate the fibrotic tissue. Moreover, the influence of sample staining on calcium, manganese, copper, and zinc distribution was also investigated. The distribution of iron specifically seems to be helpful in recognizing a damaged myocardium.

Keywords

myocardial fibrosis; rat model; soft tissue analysis; LA-ICP-MS; element distribution

Authors

MACHALOVÁ, M.; VAŠINOVÁ GALIOVÁ, M.; STRAČINA, T.

Released

8. 9. 2023

ISBN

1336-7242

Periodical

ChemZi

Number

State

Slovak Republic

BibTex

@misc{BUT184993,
  author="MACHALOVÁ, M. and VAŠINOVÁ GALIOVÁ, M. and STRAČINA, T.",
  title="LA-ICP-MS in medical research",
  year="2023",
  journal="ChemZi",
  number="1",
  issn="1336-7242",
  note="abstract"
}