Publication detail
Analysis of chemotherapeutics in extracellular vesicles
KOŽNAROVÁ, S. ZELINOVÁ, K. VAŠINOVÁ GALIOVÁ, HRSTKA, R. VONKA, P M. COUFALÍK, P. ZVĚŘINA, O.
Original Title
Analysis of chemotherapeutics in extracellular vesicles
Type
conference proceedings
Language
English
Original Abstract
The ICP-MS method proved to be appropriate for further research on cell-to-cell communication. From our results we may conclude that the naturally resistant SK-OV-3 cell line probably uses the mechanism of chemotherapeutic drug excretion from the cells by exosomes. In comparison, A2780cis cells also seemed to secrete exosomes abundantly, but at the same time with lower influx efficiency. Based on this fact, it can be assumed that A2780cis has a different resistance mechanism compared to SK-OV-3.
Keywords
CANCER; CHEMOTHERAPEUTICS; EXOSOMES; ICP-MS
Authors
KOŽNAROVÁ, S.; ZELINOVÁ, K.; VAŠINOVÁ GALIOVÁ, HRSTKA, R.; VONKA, P; M.; COUFALÍK, P.; ZVĚŘINA, O.
Released
4. 9. 2022
ISBN
978-80-88195-41-2
Book
BOOK OF ABSTRACTS ESAS 2022
BibTex
@proceedings{BUT182195,
editor="KOŽNAROVÁ, S. and ZELINOVÁ, K. and VAŠINOVÁ GALIOVÁ, HRSTKA, R. and VONKA, P and M. and COUFALÍK, P. and ZVĚŘINA, O.",
title="Analysis of chemotherapeutics in extracellular vesicles",
year="2022",
isbn="978-80-88195-41-2"
}