Publication detail

Polyhydroxyalkanoates synthesis by halophiles and thermophiles: towards sustainable production of microbial bioplastics

OBRUČA, S. DVOŘÁK, P. SEDLÁČEK, P. KOLLER, M. SEDLÁŘ, K. PERNICOVÁ, I. ŠAFRÁNEK, D.

Original Title

Polyhydroxyalkanoates synthesis by halophiles and thermophiles: towards sustainable production of microbial bioplastics

Type

journal article in Web of Science

Language

English

Original Abstract

Polyhydroxyalkanoates (PHA) are microbial polyesters produced by numerous prokaryotes. These materials are generally considered to be renewable and biodegradable alternatives to petrochemical polymers in numerous applications. PHA are accumulated by microbial cells in form of intracellular granules primarily as storage compounds; nevertheless, numerous recent reports also highlight the importance of PHA for the stress robustness of bacteria. Therefore, in this review, we focus on summarizing current knowledge on PHA accumulation in halophiles and thermophiles – prokaryotic microorganisms adapted to high salinity and high temperature, respectively. Utilization of extremophiles for PHA production brings numerous benefits stemming especially from the enhanced robustness of the process against contamination by common mesophilic microflora as a basement of the Next-Generation Industrial Biotechnology concept. Further, recent advances and future perspectives in metabolic engineering and synthetic biology of halophiles and thermophiles for PHA production improvement are also summarized and suggested. Facts and ideas gathered in this review hold a promise that biotechnological production of PHA by extremophiles can be sustainable and economically feasible enabling PHA to enter the market massively and compete with non-biodegradable petrochemical polymers in suitable applications.

Keywords

Adaptation; Archaea; Bacteria; Biotechnological production of polyhydroxyalkanoates; Halophiles; Metabolic engineering and synthetic biology; Polyhydroxyalkanoates; Stress robustness; Thermophiles

Authors

OBRUČA, S.; DVOŘÁK, P.; SEDLÁČEK, P.; KOLLER, M.; SEDLÁŘ, K.; PERNICOVÁ, I.; ŠAFRÁNEK, D.

Released

1. 9. 2022

Publisher

Elsevier Inc.

ISBN

0734-9750

Periodical

BIOTECHNOLOGY ADVANCES

Year of study

58

Number

9

State

United Kingdom of Great Britain and Northern Ireland

Pages from

1

Pages to

28

Pages count

28

URL

https://www.sciencedirect.com/science/article/pii/S0734975022000027?via%3Dihub

BibTex

@article{BUT177466,
  author="Stanislav {Obruča} and Pavel {Dvořák} and Petr {Sedláček} and Martin {Koller} and Karel {Sedlář} and Iva {Buchtíková} and David {Šafránek}",
  title="Polyhydroxyalkanoates synthesis by halophiles and thermophiles: towards sustainable production of microbial bioplastics",
  journal="BIOTECHNOLOGY ADVANCES",
  year="2022",
  volume="58",
  number="9",
  pages="1--28",
  doi="10.1016/j.biotechadv.2022.107906",
  issn="0734-9750",
  url="https://www.sciencedirect.com/science/article/pii/S0734975022000027?via%3Dihub"
}