Publication detail

Freeze-drying transparent hydrogel films from natural guma Karaya modified with octenidine dihydrochloride for infected wound healing

ČERNÁ, E. VOJTOVÁ, L. LIPOVÝ, B.

Original Title

Type

abstract

Language

English

Original Abstract

Wound healing is a process which requires an appropriate approach for effective and accelerated healing. Variety of materials including natural and synthetic polymers are used for the production of films, gels, hydrogels or sponges. Gum Karaya (GK) is a natural polymer, resin able to form a gel with antimicrobial properties supporting the healing process1. Here, GK was modified with synthetic hydrophilic gelling polymers and emollient component to obtain soft, elastic and transparent film via freeze-drying technique. To increase antimicrobial activity an antiseptic agent octenidine dihydrochloride (OCT) was added due to its antimicrobial effect, low absorption to the skin and no systemic toxicity. OCT is widely used antiseptics for topical wounds (acute, chronic) with antimicrobial effect against Gram-positive and Gram-negative bacteria including resistant pathogens.

Keywords

biopolymers, wound healing, Karaya gum, antimicrobial, tissue engineering

Authors

ČERNÁ, E.; VOJTOVÁ, L.; LIPOVÝ, B.

Released

19. 5. 2021

Publisher

CZECH CHEMICAL SOCIETY SYMPOSIUM SERIES

ISBN

2336-7210

Periodical

Czech Chemical Society Symposium Series

State

Czech Republic

Pages from

Pages to

Pages count

URL

http://www.interdisciplinarymeeting.cz/2021/shell/sbornik-2021.pdf

BibTex

@misc{BUT175301,
  author="Eva {Černá} and Lucy {Vojtová} and Břetislav {Lipový}",
  title="Freeze-drying transparent hydrogel films from natural guma Karaya modified with octenidine dihydrochloride for infected wound healing",
  year="2021",
  journal="Czech Chemical Society Symposium Series",
  pages="10--10",
  publisher="CZECH CHEMICAL SOCIETY SYMPOSIUM SERIES",
  issn="2336-7210",
  url="http://www.interdisciplinarymeeting.cz/2021/shell/sbornik-2021.pdf",
  note="abstract"
}