Publication detail

Evolutionary Engineering of Selected Polyhydroxyalkanoate Producing Strains to Biotechnologically Relevant Stressors

NOVÁČKOVÁ, I. HRABALOVÁ, V. SLANINOVÁ, E. SEDLÁČEK, P. POŘÍZKA, J. KALINA, M. SAMEK, O. OBRUČA, S.

Original Title

Evolutionary Engineering of Selected Polyhydroxyalkanoate Producing Strains to Biotechnologically Relevant Stressors

Type

abstract

Language

English

Original Abstract

Polyhydroxyalkanoates (PHAs) are microbial polymers which could replace traditional petrochemical plastics due to their favorable properties such as biodegradability and biocompatibility. Moreover, properties of PHAs depend on monomer composition therefore materials for selected purpose could be produced. Application of approaches of evolutionary engineering could be used to obtain microorganisms producing PHAs with required properties. Method is useful, quite simple and effective for gaining microbial strains with suitable characteristics on phenotype level (e.g. more effective growth, better productivity, ability of utilization different sources of carbon etc.) with no requirement for knowledge of genetic characteristics of original wild-type strain. In different point of view evolutionary experiments are relatively time-consuming and screening of huge amount of evolved phenotypes is necessary.

Keywords

evolutionary engineering, C. necator H16, H. halophila, PHA

Authors

NOVÁČKOVÁ, I.; HRABALOVÁ, V.; SLANINOVÁ, E.; SEDLÁČEK, P.; POŘÍZKA, J.; KALINA, M.; SAMEK, O.; OBRUČA, S.

Released

29. 9. 2021

ISBN

1307-6892

Periodical

World Academy of Science, Engineering and Technology

State

Republic of Turkey

Pages from

76

Pages to

76

Pages count

1

URL

https://attachments.waset.org/21/ebooks/september-2021-in-dubai-2021-09-29-10-43-51.pdf?fbclid=IwAR3lMvc3pbQQ-7IIaHj5mrz6VtHpVxX9818PXlVCHt_GwzPcWeJJcZkg5hY

BibTex

@misc{BUT173142,
  author="Ivana {Nováčková} and Vendula {Hrabalová} and Eva {Slaninová} and Petr {Sedláček} and Jaromír {Pořízka} and Michal {Kalina} and Ota {Samek} and Stanislav {Obruča}",
  title="Evolutionary Engineering of Selected Polyhydroxyalkanoate Producing Strains to Biotechnologically Relevant Stressors",
  year="2021",
  journal="World Academy of Science, Engineering and Technology",
  pages="76--76",
  issn="1307-6892",
  url="https://attachments.waset.org/21/ebooks/september-2021-in-dubai-2021-09-29-10-43-51.pdf?fbclid=IwAR3lMvc3pbQQ-7IIaHj5mrz6VtHpVxX9818PXlVCHt_GwzPcWeJJcZkg5hY",
  note="abstract"
}