Publication detail

Antimicrobial activity of selected plant extracts and its possibility to effect human health

Marie Vysoká, V.L. Mazzarello, G. Delogu, I. Márová

Original Title

Antimicrobial activity of selected plant extracts and its possibility to effect human health

Type

abstract

Language

English

Original Abstract

This study was designed to evaluate the antimicrobial activity and cytotoxicity of selected plant extracts and its possibility to effect human health. Herbal medicines are used widely because of their potent therapeutic efficacy, antioxidant activities and no side effects. In this study, tested samples of herbs were prepared as water extracts and essential oils. All extracts were prepared from dry samples of Curcumin, Euterpe oleracea, Origanum vulgare, Panax Ginseng, Syzygium aromaticum and Zingiber officinale. Antimicrobial effect was tested on Staphylococcus aureus, Candida glabrata and Escherichia coli. Cytotoxicity was tested in by colorimetric MTT test on keratinocytes HaCaT and B16F1 and also on other cell lines, e.g. Caco-2, Raji. In all extracts was detected concentration dependent antimicrobial effect. Apoptosis, the cell’s natural mechanism for death, is a promising target for anticancer therapy. The hallmarks of cancer are present in all cancer cells regardless of the cause or type; these include uncontrolled growth, angiogenesis and apoptosis evasion. The prevention of cancer is one of the main functions of apoptosis. In this study was tested the apoptotic effects of selected plant extracts of Raji cell lines.

Keywords

antimicrobial activity, Caco - 2, Raji, Mtt test, apoptosis

Authors

Marie Vysoká, V.L. Mazzarello, G. Delogu, I. Márová

Released

26. 2. 2021

Publisher

Biotechnology & Biotechnological Equipment, Volume 35, Issue sup1 (2021)

ISBN

1314-3530

Periodical

Biotechnology and Biotechnological Equipment

Number

35(1)

State

United Kingdom of Great Britain and Northern Ireland

Pages from

25

Pages to

26

Pages count

1

URL

https://eurobiotech2020.eu/

BibTex

@misc{BUT169841,
  author="Marie {Vysoká} and Ivana {Márová}",
  title="Antimicrobial activity of selected plant extracts and its possibility to effect human health",
  year="2021",
  journal="Biotechnology and Biotechnological Equipment",
  number="35(1)",
  pages="25--26",
  publisher="Biotechnology & Biotechnological Equipment, Volume 35, Issue sup1 (2021)",
  doi="10.1080/13102818.2020.1871545",
  issn="1314-3530",
  url="https://eurobiotech2020.eu/",
  note="abstract"
}