Publication detail

Preparation and characterisation of functionalized wound dressings

DZURICKÁ, L. BENDOVÁ, A. HOOVÁ, J. MATOUŠKOVÁ, P. MÁROVÁ, I.

Original Title

Preparation and characterisation of functionalized wound dressings

Type

abstract

Language

English

Original Abstract

This work is focused on preparation and characterization of bio-active hydrogels and nanofiber wound dressings functionalized by active compound in the form of antibiotic drug: ampicillin. Nano-fiber dressings were constituted from poly(3-hydroxybutyrate) and hydrogel dressings were created using alginate and chitosan. Prepared wound dressings were tested for possible cytotoxic ef-fects on human cells, antimicrobial activity and the rate of gradual releasing of the incorporated substance into model environments.Nanofibers were assembled by electrospinning and force spin-ning techniques. Morphology of the prepared nanofibers was con-firmed by SEM. Dressings were characterized for gradual release using spectrophotometric methods. Antimicrobial activity against gram-positive and gram-negative strains of microorganisms was also evaluated. the results showed good antimicrobial efficacy of functionalized materials.

Keywords

wound dressings, ampicillin, poly(3‑hydroxybutyrate), chitosan, alginate, antimicrobial activity, cytotoxicity

Authors

DZURICKÁ, L.; BENDOVÁ, A.; HOOVÁ, J.; MATOUŠKOVÁ, P.; MÁROVÁ, I.

Released

26. 11. 2020

Publisher

Vysoké učení technické v Brně, Fakulta chemická

Location

Brno

ISBN

978-80-214-5920-0

Book

Studentská odborná konference CHEMIE JE ŽIVOT 2020 Sborník abstraktů

Edition number

první

Pages from

59

Pages to

60

Pages count

164

URL

https://www.fch.vut.cz/vav/konference/sok/vystupy/sbornik-abstrakty-konference-2020-pdf-p198641

BibTex

@misc{BUT166180,
  author="Lucia {Dzurická} and Agáta {Bendová} and Julie {Hoová} and Petra {Skoumalová} and Ivana {Márová}",
  title="Preparation and characterisation of functionalized wound dressings",
  booktitle="Studentská odborná konference CHEMIE JE ŽIVOT 2020 Sborník abstraktů",
  year="2020",
  edition="první",
  pages="59--60",
  publisher="Vysoké učení technické v Brně, Fakulta chemická",
  address="Brno",
  isbn="978-80-214-5920-0",
  url="https://www.fch.vut.cz/vav/konference/sok/vystupy/sbornik-abstrakty-konference-2020-pdf-p198641",
  note="abstract"
}