Publication detail

Chitosan-glucan Complex Hollow Fibers Reinforced Collagen Wound Dressing Embedded with Aloe vera. Part I: Preparation and Characterization

ABDELLATIF, A. ABDELRAHMAN, R. KUBĚNA, I. KOBĚRA, L. SPOTZ, Z. ZBONČÁK, M. PŘIKRYL, R. BRUS, J. JANČÁŘ, J.

Original Title

Chitosan-glucan Complex Hollow Fibers Reinforced Collagen Wound Dressing Embedded with Aloe vera. Part I: Preparation and Characterization

Type

journal article in Web of Science

Language

English

Original Abstract

Collagen (CO)/chitosan-glucan complex (CSGC) hollow fibers encapsulated aloe vera (AV) dressing scaffold (CO/CSGC@AV) were fabricated for the first time by the freeze-dried process. Extraction process, morphology, mechanical properties, pore size, porosity, swelling ability, and degradation behavior of composites scaffold were investigated. CSGC hollow fibers were extracted from mycelium of Schizophyllum commune CSGC hollow fiber exhibited inner diameter of (600 ± 250 nm) and outer fiber diameter of (2.5 ± 0.5 µm). The results of swelling and hydrolytic degradation studies demonstrated that the physicochemical of CO/CSGC@AV was significantly enhanced by CSGC in a concentration-dependent manner. The mechanical property of the CO/CSGC@AV was improved after encapsulated AV into CSGC hollow fibers compared with native CO. The pore size and porosity of the CO/CSGC@AV were slightly decreased in the presence of AV. All these results suggested that the new dressing scaffold has a potential for clinical skin regeneration, particularly for infected chronic wounds and ulcers.

Keywords

Chitosan-glucan, hollow fiber, collagen, aloe vera, degradation, release properties

Authors

ABDELLATIF, A.; ABDELRAHMAN, R.; KUBĚNA, I.; KOBĚRA, L.; SPOTZ, Z.; ZBONČÁK, M.; PŘIKRYL, R.; BRUS, J.; JANČÁŘ, J.

Released

15. 2. 2020

ISBN

0144-8617

Periodical

Carbohydrate Polymers

Year of study

5

Number

25

State

United Kingdom of Great Britain and Northern Ireland

Pages from

101

Pages to

117

Pages count

15

URL

https://www.sciencedirect.com/science/article/pii/S0144861719313761

BibTex

@article{BUT160710,
  author="ABDELLATIF, A. and ABDELRAHMAN, R. and KUBĚNA, I. and KOBĚRA, L. and SPOTZ, Z. and ZBONČÁK, M. and PŘIKRYL, R. and BRUS, J. and JANČÁŘ, J.",
  title="Chitosan-glucan Complex Hollow Fibers Reinforced Collagen Wound Dressing Embedded with Aloe vera. Part I: Preparation and Characterization",
  journal="Carbohydrate Polymers",
  year="2020",
  volume="5",
  number="25",
  pages="101--117",
  doi="10.1016/j.carbpol.2019.115708",
  issn="0144-8617",
  url="https://www.sciencedirect.com/science/article/pii/S0144861719313761"
}