Publication detail

Collagen-phosphate porous scaffolds for novel bone tissue engineering concept

BRTNÍKOVÁ, J. PAVLIŇÁKOVÁ, V. ŠŤASTNÝ, P. TRUNEC, M. POLÁČEK, P. BLAHNOVÁ, V. FILOVA, E. VOJTOVÁ, L.

Original Title

Type

abstract

Language

English

Original Abstract

In this work, the bovine collagen type I was combined with calcium phosphates differing in solubility and resorbability. The effect of bioceramics solubility and particle sizes on scaffolds morphology, biomechanics, physical and biological properties was observed. Addition of bioceramic particles changed morphology of the samples resulting in decreasing the pore size, while the porosity becomes nearly the same in all tested samples. The biomechanical properties of the samples were tested in both dry and hydrated state. In dry state, collagen scaffolds reached the highest compressive strength, in contrary to the hydrated state, where samples containing bioceramic particles were stiffer but the strength values were one order lower comparing to samples in dry state. During in-vitro experiments, none of samples was found to be cytotoxic.

Keywords

collagen scaffold, hydroxyapatite, α- and β-tricalcium phosphate

Authors

BRTNÍKOVÁ, J.; PAVLIŇÁKOVÁ, V.; ŠŤASTNÝ, P.; TRUNEC, M.; POLÁČEK, P.; BLAHNOVÁ, V.; FILOVA, E.; VOJTOVÁ, L.

Released

3. 12. 2018

Publisher

iMedPub LTD

Location

London, UK

ISBN

2394-9988

Periodical

International Journal of Applied Science-Research and Review

Year of study

Number

State

United Kingdom of Great Britain and Northern Ireland

Pages from

Pages to

Pages count

BibTex

@misc{BUT159489,
  author="Jana {Brtníková} and Veronika {Pavliňáková} and Přemysl {Šťastný} and Martin {Trunec} and Petr {Poláček} and Veronika {Blahnová} and Eva {Filova} and Lucy {Vojtová}",
  title="Collagen-phosphate porous scaffolds for novel bone tissue engineering concept",
  year="2018",
  journal="International Journal of Applied Science-Research and Review",
  volume="C2",
  number="5",
  pages="29--29",
  publisher="iMedPub LTD",
  address="London, UK",
  doi="10.21767/2394-9988-C2-006",
  issn="2394-9988",
  note="abstract"
}