Publication detail

The Use of Bioactive Compounds and Their Encapsulation into Liposomes to Increase the Effectiveness and Control Release

HOOVÁ, J. VYSOKÁ, M. DZURICKÁ, L. MATOUŠKOVÁ, P. MÁROVÁ, I.

Original Title

Type

abstract

Language

English

Original Abstract

The aim of this work is to encapsulate microbial compounds, some plant extracts and also model hydrophilic and hydrophobic substances. Chosen components were encapsulated into liposomes. Particle size and distributions of liposomes were analyzed by dynamic light scattering and their stability by using zeta potential. Spectrophotometric methods were used to measure encapsulation efficiency and to characterize the chosen plant extracts by its amount of total polyphenols, flavonoids and antioxidant activity. Chosen samples were analyzed for their antimicrobial activity and cytotoxicity. Serratia marcescens, Escherichia coli as gram-negative bacterias, Micrococcus luteus as gram-positive bacteria and fungal strain (Candida glabrata) were used to test antimicrobial activity. Human keratinocytes and mouse melanoma cells were used to cytotoxicity determination.

Keywords

Encapsulation, liposomes, polyphenols, antioxidant activity, antimicrobial activity, cytotoxicity

Authors

HOOVÁ, J.; VYSOKÁ, M.; DZURICKÁ, L.; MATOUŠKOVÁ, P.; MÁROVÁ, I.

Released

17. 10. 2018

Publisher

TANGER Ltd.

Location

Ostrava

ISBN

978-80-87294-85-7

Book

Nanocon - Abstracts

Edition

Pages from

103

Pages to

103

Pages count

BibTex

@misc{BUT155283,
  author="Julie {Hoová} and Marie {Vysoká} and Lucia {Dzurická} and Petra {Skoumalová} and Ivana {Márová}",
  title="The Use of Bioactive Compounds and Their Encapsulation into Liposomes to Increase the Effectiveness and Control Release",
  booktitle="Nanocon - Abstracts",
  year="2018",
  series="1",
  pages="103--103",
  publisher="TANGER Ltd.",
  address="Ostrava",
  isbn="978-80-87294-85-7",
  note="abstract"
}