Publication detail

Adaptation of PHA producing bacteria to levulinic acid

KUČERA, D. NOVÁČKOVÁ, I. PERNICOVÁ, I. OBRUČA, S.

Original Title

Adaptation of PHA producing bacteria to levulinic acid

Type

conference paper

Language

English

Original Abstract

Polyhydroxyalkanoates (PHAs) are bacterial polyesters which are considered as biodegradable and environmentally-friendly alternative to petrochemical plastics. Poly-3-hydroxybutyrate is typical but in the plastics industry, the copolymer of poly-3-hydroxybutyrate-co-3-hydroxyvalerate (P3HB-co-3HV) is significantly better utilized due to its material properties. The aim was to use the concept of evolutionary engineering to obtain strains capable of utilization levulinic acid for production P3HB-co-3HV. Adaptation tests were carried out with the Cupriavidus necator H16 strain. Higher LA concentrations have been shown to significantly reduce the growth of the selected strain. Adaptation tests led to an increase in the proportion of PHV in the copolymer produced.

Keywords

polyhydroxyalkanoates, stress, levulinic acid, adaptation, evolutionary engineering

Authors

KUČERA, D.; NOVÁČKOVÁ, I.; PERNICOVÁ, I.; OBRUČA, S.

Released

21. 11. 2018

Publisher

Czech Society of Industrial Chemistry

Location

Prague

ISBN

978-80-86238-77-7

Book

Proceedings of the 6th International Conference on Chemical Technology

Edition

1st edition

ISBN

2336-8128

Periodical

International Conference on Chemical Technology

State

Czech Republic

Pages from

74

Pages to

77

Pages count

4

URL

http://www.icct.cz/AngiologyKlon-ICCT/media/system/2018/ICCT-2018-Proceedings.pdf

BibTex

@inproceedings{BUT151361,
  author="Dan {Kučera} and Ivana {Nováčková} and Iva {Buchtíková} and Stanislav {Obruča}",
  title="Adaptation of PHA producing bacteria to levulinic acid",
  booktitle="Proceedings of the 6th International Conference on Chemical Technology",
  year="2018",
  series="1st edition",
  journal="International Conference on Chemical Technology",
  pages="74--77",
  publisher="Czech Society of Industrial Chemistry",
  address="Prague",
  isbn="978-80-86238-77-7",
  issn="2336-8128",
  url="http://www.icct.cz/AngiologyKlon-ICCT/media/system/2018/ICCT-2018-Proceedings.pdf"
}