Publication detail

Effect of counterion on rheological properties of hydrogels prepared from hyaluronan and oppositely charged surfactant

VELCER, T. PEKAŘ, M.

Original Title

Type

conference paper

Language

English

Original Abstract

This study deals with the properties and behaviour of phase-separated hydrogels prepared by interaction of hyaluronan (Hya) with oppositely charged surfactants. Three representatives of surfactants, namely cetyltrimethylammonium bromide, chloride and p-toluensulfonate (CTAB, CTAC, CTAT), were selected for comparison. Using the method of rheology, the fact that the system of Hya-CTAT forms the most rigid hydrogels has been proved. Higher molecular weight of hyaluronan has also direct influence on the volume and stiffness of the newly formed hydrogels. Preparation methods were compared as well. Mixing the stock solutions of entry components appeard to be the most suitable. The results of this study indicate that given gels are to a certain extent competitive and incorporation of hyaluronan into their structure is desirable with respect to its biological activity. This offers a potential usage of these substances in the field of medical applications.

Keywords

hyaluronan, surfactants, hydrogels, rheology

Authors

VELCER, T.; PEKAŘ, M.

Released

23. 3. 2017

Publisher

Vysoké učení technické v Brně, Fakulta chemická

Location

Brno

ISBN

978-80-214-5489-7

Book

Sborník příspěvků

Edition

Edition number

první

Pages from

218

Pages to

223

Pages count

BibTex

@inproceedings{BUT140071,
  author="Tomáš {Velcer} and Miloslav {Pekař}",
  title="Effect of counterion on rheological properties of hydrogels prepared from hyaluronan and oppositely charged surfactant",
  booktitle="Sborník příspěvků",
  year="2017",
  series="1.",
  number="první",
  pages="218--223",
  publisher="Vysoké učení technické v Brně, Fakulta chemická",
  address="Brno",
  isbn="978-80-214-5489-7"
}