Publication detail
Using UV-VIS spectrophotometry for determining ecotoxicity of selected non-steroidal anti-inflammatory drugs
ČAPKA, L. ZLÁMALOVÁ GARGOŠOVÁ, H. VÁVROVÁ, M.
Original Title
Using UV-VIS spectrophotometry for determining ecotoxicity of selected non-steroidal anti-inflammatory drugs
Type
journal article in Web of Science
Language
English
Original Abstract
This paper presents the use of UV-VIS spectrophotometry as a means of determining ecotoxicity. The method is based on spectrophotometric measuring of micro-algae Pseudokirchneriella subcapitata in water suspension. Six non-steroidal anti-inflammatory drugs (paracetamol, diclofenac, salicylic acid, ibuprofen, naproxen and ketoprofen) were selected as target compounds because they are the most commonly used human pharmaceuticals, which also means they are significant environmental pollutants. The 72hEC50 method was chosen for determination of ecotoxicity. The results reveal paracetamol (104 mg/L) and particularly ketoprofen (9 mg/L) as potentially ecotoxic compounds for aquatic organisms.
Keywords
Ecotoxicity, non-steroidal anti-inflammatory drugs, UV-VIS spectrophotometry
Authors
ČAPKA, L.; ZLÁMALOVÁ GARGOŠOVÁ, H.; VÁVROVÁ, M.
RIV year
2015
Released
1. 12. 2015
ISBN
1018-4619
Periodical
Fresenius Environmental Bulletin
Year of study
24
Number
12
State
Federal Republic of Germany
Pages from
4758
Pages to
4762
Pages count
5
BibTex
@article{BUT119157,
author="Lukáš {Alexa} and Helena {Zlámalová Gargošová} and Milada {Vávrová}",
title="Using UV-VIS spectrophotometry for determining ecotoxicity of selected non-steroidal anti-inflammatory drugs",
journal="Fresenius Environmental Bulletin",
year="2015",
volume="24",
number="12",
pages="4758--4762",
issn="1018-4619"
}