Publication detail

The Thermodynamic Driving Force for Kinetics in General and Enzyme Kinetics in Particular

PEKAŘ, M.

Original Title

Type

journal article in Web of Science

Language

English

Original Abstract

The thermodynamic driving force of a reaction is usually taken as the chemical potential difference between products and reactants. The forward and backward reaction rates are then related to this force. This procedure is of very limited validity, the resulting expression contains no kinetic factor and gives little information on reaction kinetics. The transformation of the reaction rate as a function of concentration (and temperature) into a function of chemical potential should be more properly performed as illustrated by a simple example of an enzymatic reaction. The proper thermodynamic driving force is the difference between the exponentials of the totaled chemical potentials of reactants and products.

Keywords

driving force, kinetics, reaction rate, thermodynamics

Authors

PEKAŘ, M.

RIV year

2015

Released

2. 3. 2015

ISBN

1439-4235

Periodical

CHEMPHYSCHEM

Year of study

Number

State

Federal Republic of Germany

Pages from

884

Pages to

885

Pages count

BibTex

@article{BUT113928,
  author="Miloslav {Pekař}",
  title="The Thermodynamic Driving Force for Kinetics in General and Enzyme Kinetics in Particular",
  journal="CHEMPHYSCHEM",
  year="2015",
  volume="16",
  number="4",
  pages="884--885",
  issn="1439-4235"
}