Publication detail

Synthesis and antibacterial activity of 3-arylidene chromen-2, 4-dione derivatives

MOHAMED, F. SOLIMAN, A. ABDEL-MOTALEB, R. ABDEL-RAHMAN, R. ABDEL-LATTIF, A. FOUDA, M. AL-DEYAB, S. MOHAMED, A.

Original Title

Type

journal article - other

Language

English

Original Abstract

Derivatives of 3-arylidene chromen-2, 4-dione 1 were synthesized to be used as a starting material for synthesizing some new fused heterocyclic compounds containing coumarin moiety. When compounds 1 reacted with hydrazine derivatives, hydroxylamine hydrochloride, urea, thiourea, semicarbazide and thiosemicarbazide it gave the corresponding compounds 2-5. Compound 4a, b reacted with methyl iodide in DMF and K2CO3 at room temperature to afford the corresponding 6a, b. All these compounds were screened InVitro for their antibacterial activity.

Keywords

Coumarin, hydrazine, pyrazol, isoxazol, pyrimidine and antibacterial activity

Authors

MOHAMED, F.; SOLIMAN, A.; ABDEL-MOTALEB, R.; ABDEL-RAHMAN, R.; ABDEL-LATTIF, A.; FOUDA, M.; AL-DEYAB, S.; MOHAMED, A.

RIV year

2013

Released

7. 11. 2013

ISBN

1097-8135

Periodical

Life Science Journal

Year of study

Number

State

People's Republic of China

Pages from

840

Pages to

845

Pages count

BibTex

@article{BUT106169,
  author="F. K. {Mohamed} and A. Y. {Soliman} and Ramadan M. {Abdel-Motaleb} and Rasha M. {Abdel-Rahman} and Abdelmohsen Moustafa {Abdellatif} and Moustafa M.D. {Fouda} and Salem S. {Al-Deyab} and Asmaa S. {Mohamed}",
  title="Synthesis and antibacterial activity of 3-arylidene chromen-2, 4-dione derivatives",
  journal="Life Science Journal",
  year="2013",
  volume="10",
  number="4",
  pages="840--845",
  issn="1097-8135"
}