Publication detail

Colloid Properties of Ultrasound Contrast Agents

PILGROVÁ, T. MRAVEC, F. PEKAŘ, M. HAVLÍNOVÁ, J. ORBAN, M.

Original Title

Type

abstract

Language

English

Original Abstract

Microbubbles are used in biomedical field as diagnostic agents in combination with ultrasound. This imaging technique has also been proposed for drug or gene delivery to targeted regions. The aim of our study was to identify the potential of ultrasound agent SonoVue(R) for drug delivery. The properties of SonoVue(R) were investigated by dynamic light scattering method, centrifugal dispersion analysis and fluorescence spectroscopy measurement. Ability of incorporation of drug was studied with doxorubicin hydrochloride and hydrophobic fluorescent probe. We present results of a pilot study to determine colloid properties of SonoVue(R) microbubble suspension. The results will be used in subsequent experiments and for design a new drug delivery system.

Keywords

microbubble, drug delivery, SonoVue(R)

Authors

PILGROVÁ, T.; MRAVEC, F.; PEKAŘ, M.; HAVLÍNOVÁ, J.; ORBAN, M.

Released

5. 9. 2013

ISBN

1364-5706

Periodical

MINIMALLY INVASIVE THERAPY & ALLIED TECHNOLOGIES

Year of study

Number

State

Kingdom of Norway

Pages from

Pages to

Pages count

BibTex

@misc{BUT105632,
  author="Tereza {Pilgrová} and Filip {Mravec} and Miloslav {Pekař} and Jana {Havlínová} and Marek {Orban}",
  title="Colloid Properties of Ultrasound Contrast Agents",
  year="2013",
  journal="MINIMALLY INVASIVE THERAPY & ALLIED TECHNOLOGIES",
  volume="22",
  number="1",
  pages="46--47",
  issn="1364-5706",
  note="abstract"
}