This project is dedicated to the proposal, characterization and optimization of conductive polymers-based hydrogels for bioelectronics and biomedicine. The design of new materials based on counterions directly bound to PEDOT will be based on advanced characterization and understanding of electronic and ionic processes related to the charge transport in these hydrogels. Ionic currents were found to be critical for tissue repair upon wounding. As a proof of concept a model bioelectronic device for regeneration of epithelium and vascular endothelium will be carried out. The role of conductive hydrogel material per se as well as the electrostimulation with this material will be studied. The three main objectives of the project are: i) propose and develop novel conductive hydrogels for bioelectronics and biomedicine, ii) contribute to the understanding of elementary electron and ion processes related to the charger transport in hydrogels, and iii) propose a bioelectronic device based on hydrogel to modulate cell layer regeneration and vascularization.

Keywords
conductive hydrogels;PEDOT;charge transport;electronic and ionic processes;biomedical applications

24-10469S

English

Weiter Martin, prof. Ing., Ph.D. - principal person responsible

Materials Research Centre
- responsible department (4.4.2023 - not assigned)
Materials Research Centre
- beneficiary (4.4.2023 - not assigned)

MALEČKOVÁ, R.; TUMOVÁ, Š.; SMÍSITEL, P.; SMILEK, J.; ŠIMŮNKOVÁ, H.; PEŠKOVÁ, M.; KUBÁČ, L.; HUBÁLEK, J.; VÍTEČEK, J.; VALA, M.; WEITER, M. Novel conductive PEDOT:DBSA hydrogels with tuneable properties for bioelectronics. Materials Advances, 2025, vol. 6, no. 4, p. 1278-1287. ISSN: 2633-5409.
Detail

MARKOVÁ, A.; BYUN, D.; ZHIVKOV, I.; VÍTEČEK, J.; BINTINGER, J.; WEITER, M.; VALA, M. Real-time Study of Ion Exchange and Transport in Organic Bioelectronic Devices. 9th Meeting on Chemistry & Life for Sustainable Future: Book of Abstracts. Brno, Česká republika: Vysoké učení technické v Brně, Fakulta chemická, 2024. p. 94-94.
Detail

MARKOVÁ, A.; BYUN, D.; ZHIVKOV, I.; VÍTEČEK, J.; BINTINGER, J.; WEITER, M.; VALA, M. Combined Detection Method as a New Approach for the Selective Study of Ion Exchange and Transport in Organic Bioelectronic Devices. 9th Meeting on Chemistry & Life for Sustainable Future: Book of Abstracts. Brno, Česká republika: Vysoké učení technické v Brně, Fakulta chemická, 2024. p. 101-101.
Detail

MARKOVÁ, A.; BYUN, D.; WEITER, M.; BINTINGER, J.; VALA, M. Direct Combined Determination of Ion Transport and Exchange in Organic Bioelectronic Devices. Abstract Book (PDF). Boston, USA: Materials Research Society, 2024. p. 2309-2310.
Detail

MARKOVÁ, A.; TUMOVÁ, Š.; MALEČKOVÁ, R.; POSPÍŠIL, J.; SMILEK, J.; KUBÁČ, L.; AKRMAN, J.; PEŠKOVÁ, M.; VÍTEČEK, J.; HUBÁLEK, J.; VALA, M.; WEITER, M. Hydrogel Based Organic Electrochemical Transistors. 9th International Winterschool on Bioelectronics BioEl 2024 Program and book of abstracts. Kirchberg in Tirol, Austria: Johannes Kepler University Linz, Linz Institute for Organic Solar Cells, 2024. p. 93-93.
Detail

MALEČKOVÁ, R.; TUMOVÁ, Š.; MARKOVÁ, A.; POSPÍŠIL, J.; SMILEK, J.; PEŠKOVÁ, M.; KUBÁČ, L.; VÍTEČEK, J.; VALA, M.; WEITER, M. Conducting Hydrogel with Tunable Properties Based on PEDOT:DBSA for Applications in Bioelectronics. Linz, Rakousko: JKU Linz, 2024. p. 92-92.
Detail

Responsibility: Weiter Martin, prof. Ing., Ph.D.