Smart 4D printed hydrogels enriched with human dermal fibroblasts (HDF) cells promise a great application in tissue engineering to produce pharmaceuticals and medical implants. This project uses a bioresorbable hydrogel PLGA-PEG-PLGA modified with double bonds (blue-light crosslinking) and thiol groups (pH crosslinking). The possibility of crosslinking the hydrogel by stimuli after 3D printing presents the time factor of 4D printing. Cytocompatibility, stability, mechanical properties and strength of printed hydrogel carriers will be evaluated.

CEITEC VUT-J-23-8187

Czech

Tušlová Klára, Ing. - principal person responsible
Vojtová Lucy, doc. Ing., Ph.D. - fellow researcher

Advanced Biomaterials
- responsible department (6.3.2023 - not assigned)
Central European Institute of Technology BUT
- responsible department (12.1.2023 - 6.3.2023)
Advanced Biomaterials
- beneficiary (1.1.2023 - 31.12.2023)

CHAMRADOVÁ, I.; LYSÁKOVÁ, K.; KADLECOVÁ, Z.; VOJTOVÁ, L. Vývoj biokompatibilního “smart” hydrogelu uvolňujícího fibroblastový růstový faktor. III. česko-slovenský kongres "MEZIOBOROVÉ PŘÍSTUPY V HOJENÍ RAN“. Brno: SYMMA, spol. s r.o., 2023. s. 28-28. ISBN: 978-80-11-04155-7.
Detail

LYSÁKOVÁ, K.; SAHUĽ, M.; FINNE-WISTRAND, A.; VOJTOVÁ, L. Exploring the potential of 4D bioprinting of smart PLGA-PEG-PLGA based hydrogel for personalized medicine. THE TWENTY-FOURTH ANNUAL CONFERENCE YUCOMAT 2023 Program and Book of Abstracts. Belgrade: Materials Research Society of Serbia, 2023. p. 175-175. ISBN: 978-86-919111-8-8.
Detail

Responsibility: Tušlová Klára, Ing.