Detail publikace

The use of comprehensive two-dimensional gas chromatograhy with mass spectrometric detection for the assessment of drug-residue contamination of wastewater and surface water

LACINA, P. MRAVCOVÁ, L. VÁVROVÁ, M.

Originální název

Typ

abstrakt

Jazyk

angličtina

Originální abstrakt

This study is focused on application of analytical method for analysis of selected drug residues from wastewaters and surface waters. Target compounds were acidic drugs mainly from the group of non-steroidal anti-inflammatory drugs (salicylic acid, acetylsalicylic acid, clofibric acid, ibuprofen, acetaminophen, kofein, naproxen, mefenamic acid, ketoprofen, diclofenac). Detection limits of presented method were ranged from 0.18 to 5 ng/L depending on specific compound. The method was successfully applied for determination of presence and concentration of selected drug residues in Svratka river and in wastewater from WWTP in Brno. Concentrations of drug residues were ranged from units to tens of ng/L for river water and from units to tens of ug/L for wastewaters. Analytical method used in this study includes solid phase extraction (SPE), derivatization by MSTFA (N-methyl-N-(trimethylsilyl)trifluoroacetamide) and final analysis by orthogonal comprehensive two-dimensional gas chromatography with mass spectrometric detection Time-of-Flight (GCxGC-TOF MS).

Klíčová slova

drug residues, non-steroidal anti-inflammatory drugs, analgesics, GCxGC-TOF MS, wastewater, surface water

Autoři

LACINA, P.; MRAVCOVÁ, L.; VÁVROVÁ, M.

Vydáno

17. 8. 2011

Nakladatel

Fakulta chemická VUT v Brně

Místo

Brno

ISSN

0009-2770

Periodikum

Chemické listy

Ročník

105

Stát

Česká republika

Strany od

964

Strany do

965

Strany počet

BibTex

@misc{BUT73326,
  author="Petr {Lacina} and Ludmila {Mravcová} and Milada {Vávrová}",
  title="The use of comprehensive two-dimensional gas chromatograhy with mass spectrometric detection for the assessment of drug-residue contamination of wastewater and surface water",
  booktitle="5th Meeting on Chemistry and Life: Book of Abstracts",
  year="2011",
  journal="Chemické listy",
  volume="105",
  pages="964--965",
  publisher="Fakulta chemická VUT v Brně",
  address="Brno",
  issn="0009-2770",
  note="abstract"
}