Detail publikace
Femoral bone defect healing using two novel biocompatible degradable materials
SRNEC, R. NEČASOVÁ, A. PROKS, P. SKORIC, M. FILIPEJOVÁ, Z. VOJTOVÁ, L. NEČAS, A.
Originální název
Femoral bone defect healing using two novel biocompatible degradable materials
Typ
článek v časopise ve Web of Science, Jimp
Jazyk
angličtina
Originální abstrakt
This study was conducted as an in vivo experiment in adult miniature pigs with the aim to test two new biomaterials. An iatrogenic defect was made into the central femoral diaphysis in the experimental animals and subsequently fixated by bridging plate osteosynthesis. Into the defect we implanted a cancellous autograft (control group), a pasty injectable scaffold (EXP A), anda porous 3D cylinder (EXP B). Radiological examination was performed in all animals at 0, 10, 20, 30 weeks after surgical procedure and histological assessment was performed. In the newly formed bone the osteoblastic activity was monitored. In terms of radiology, the most effective method was observed in the control group (completely healed 100%) compared to experimental groups EXP A (70.0%) and EXP B (62.5%).
Klíčová slova
Pig, biomaterial, scaffold, animal model, composite, phosphate
Autoři
SRNEC, R.; NEČASOVÁ, A.; PROKS, P.; SKORIC, M.; FILIPEJOVÁ, Z.; VOJTOVÁ, L.; NEČAS, A.
Vydáno
26. 5. 2020
Nakladatel
Acta Veterinaria Brno
Místo
Brno
ISSN
1801-7576
Periodikum
ACTA VETERINARIA BRNO
Ročník
89
Číslo
2
Stát
Česká republika
Strany od
163
Strany do
169
Strany počet
7
URL
Plný text v Digitální knihovně
BibTex
@article{BUT166347,
author="Robert {Srnec} and Andrea {Nečasová} and Pavel {Proks} and Misa {Skoric} and Zita {Filipejová} and Lucy {Vojtová} and Alois {Nečas}",
title="Femoral bone defect healing using two novel biocompatible degradable materials",
journal="ACTA VETERINARIA BRNO",
year="2020",
volume="89",
number="2",
pages="163--169",
doi="10.2754/avb202089020163",
issn="1801-7576",
url="https://actavet.vfu.cz/89/2/0163/"
}Dokumenty