Detail publikace

Selenium containing heterocyclic: Synthesis, antimicrobial of some new selenazole Substituted phthalazin-ones

EL-SHAMY, I. ABDEL-LATTIF, A. FOUDA, M. ALMONASY, N. AL-DEYAB, S. EL-HASHASH, M.

Originální název

Typ

článek v časopise - ostatní, Jost

Jazyk

angličtina

Originální abstrakt

The principal purpose of the present study is to synthesize and investigate the antimicrobial and antifungal activities of new 1, 3-selenazole derivatives having phthalazin-1(2H)-one moieties. A multi-step reaction route was developed to synthesize a several of targeted derivatives starting from 4-alkyl/aryl-phthalazin-1(2H)-one and 2-chloro-N-phenylacetamide. The structures of the synthesized compounds were confirmed by 1HNMR, 13CNMR, MS, IR spectroscopy and by elemental analysis. The antimicrobial and antifungal activities of all derivatives against four species of bacteria and two species of fungi were investigated. The antimicrobial and antifungal activity was determined in the extracts using disk diffusion method. Amoxicillin and Ketoconazole were used as standard drugs for the bacteria and fungi, respectively.

Klíčová slova

Selenium, phthalazin-1(2H)-one, antimicrobial activity

Autoři

EL-SHAMY, I.; ABDEL-LATTIF, A.; FOUDA, M.; ALMONASY, N.; AL-DEYAB, S.; EL-HASHASH, M.

Rok RIV

2013

Vydáno

18. 10. 2013

ISSN

1097-8135

Periodikum

Life Science Journal

Ročník

Číslo

Stát

Čínská lidová republika

Strany od

799

Strany do

809

Strany počet

BibTex

@article{BUT106135,
  author="Ibrahim E. {El-Shamy} and Abdelmohsen Moustafa {Abdellatif} and Moustafa M.D. {Fouda} and Numan {Almonasy} and Salem S. {Al-Deyab} and Maher A. {El-Hashash}",
  title="Selenium containing heterocyclic: Synthesis, antimicrobial of some new selenazole Substituted phthalazin-ones",
  journal="Life Science Journal",
  year="2013",
  volume="10",
  number="4",
  pages="799--809",
  issn="1097-8135"
}