Projekt - Materiály pro integraci živočišných buněk a organické elektroniky pro budoucí biolektronické zařízení

Zdroje financování

Grantová agentura České republiky - Standardní projekty

- plně financující (2013-02-19 - 2016-12-31)

O projektu

Projekt je zaměřen na výzkum materiálů pro integraci organické elektroniky a živých buněk s cílem vytvoření znalostní základny pro příští generaci bioelektronických zařízení. V průběhu řešení projektu bude navržen princip senzoru fyziologických funkcí kardiomyocytů.

Popis anglicky
The project focuses on the exploration of the integration of organic electronic devices together with living cells in order to create a significant knowledge background for a future generation of bioelectronic devices. The approach of this project is to utilize the latest achievements of organic and molecular electronics in the biological area. To reach a proposed goal a multidisciplinary research on electronic responses of cells on external stimuli should be addressed. The main objectives of the project are: i) Optimization and deposition of organic semiconductors to be used in organic electronic devices, ii) Test of biocompatibility of thin layers of organic electronic devices, iii) Development of thin layer organic electronic devices for monitoring of the living cells, iv) Characterization of thin layer organic electronic devices as sensors for electrical potentialchanges on cell membrane of cardiomyocytes, v) Optimization and validation of newly developed organic sensor for determination of cardiomyocytes physiological functions.

Označení

GA13-29358S

Originální jazyk

čeština

Řešitelé

Weiter Martin, prof. Ing., Ph.D. - hlavní řešitel

Útvary

Fakulta chemická
- příjemce (25.02.2013 - nezadáno)

Výsledky

KRATOCHVÍLOVÁ, I.; SYCHROVSKÝ, V.; PÁV, O.; VALA, M. DNA and RNA Charge Transport Effect of Sequence, Stacking, Structure and Hg Incorporation. BIOPHYSICAL JOURNAL. Cambridge, MA 02139 USA: CELL PRESS, 2013. p. 424A (424A p.)ISSN: 0006-3495.
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STŘÍTESKÝ, S.; MARKOVÁ, A.; VÍTEČEK J.; ŠAFAŘÍKOVÁ, E.; HRABAL, M.; KUBÁČ, L.; KUBALA, L.; WEITER, M.; VALA, M.;. Printing inks of electroactive polymer PEDOT:PSS: The study of biocompatibility, stability, and electrical properties. JOURNAL OF BIOMEDICAL MATERIALS RESEARCH PART A, 2018, vol. 106, no. 4, p. 1121-1128. ISSN: 1549-3296.
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FREBORT, Š.; VALA, M.; LUŇÁK, S.; HONOVÁ, J.; MIKYSEK, T.; ELIÁŠ, Z.; LYČKA, A. Diphenylamine end-capped diketopyrrolopyrroles with phenylene–vinylene conjugation extension. TETRAHEDRON LETTERS, 2014, vol. 2014, no. 55, p. 2829-2834. ISSN: 0040-4039.
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KRATOCHVÍLOVÁ, I.; GOLAN, M.; VALA, M.; FLIMELOVÁ, M.; WEITER, M.; PÁV, O.; ŠEBERA, J.; ROSENBERG, I.; SYCHROVSKÝ, V.; TANAKA, Y.; BICKELHAUPT, F.M. Theoretical and experimental study of charge transfer through DNA: impact of mercury mediated T-Hg-T base pair. JOURNAL OF PHYSICAL CHEMISTRY B, 2014, vol. 2014, no. 118, p. 5374-5381. ISSN: 1520-6106.
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HONOVÁ, J.; STŘÍTESKÝ, S.; VALA, M.; WEITER, M. New thiophene-free diketopyrrolopyrrole derivatives for organic electronics. INTERNATIONAL FALL SCHOOL ON ORGANIC ELECTRONICS ‐ 2014 book of abstracts. Moscow, Russia: IFSOE 2014, 2014. p. 76-76.
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HEINRICHOVÁ, P.; WEITER, M.; VALA, M.; ŽITŇAN, M.; SCHMIEDOVÁ, V. The Study of Photogeneration Processes of Polymeric Solar Cells by Fluorescence Quenching Experiments. International Fall School on Organic Electronics - Book of Abstracts. Moskva: 2014.
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ZHIVKOV, I.; GEORGIEV, P.; VALA, M.; TODOROV, D.; YORDANOV, R.; WEITER, M. Wide Range Current Amplifier with Data Acquisition System. Annual Journal of Electronics, 2014, vol. 8, no. 8, p. 185-188. ISSN: 1314-0078.
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SIDEROV, V.; DOBRIKOV, G.H.; ZHIVKOV, I.; DOBRIKOV, G.M.; GEORGIEV, Y.; YORDANOV, R.; HONOVÁ, J.; WEITER, M. Photoelectrical characterization of a new low molecular weight compound. Journal of Physics: Conference Series, 2014, vol. 558, no. 012064, p. 1-6. ISSN: 1742-6596.
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OMASTA, L.; SALYK, O.; WEITER, M. Inkjet printed organic electrochemical transistors for biosensing. Studentská odborná konference Chemie je život 2014, Sborník abstraktů. Purkyňova 464/118, 612 00Brno: Vysoké učení technické v Brně, Fakulta chemická, 2014. p. 85-85. ISBN: 978-80-214-5077-6.
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OMASTA, L.; SALYK, O.; WEITER, M. Electrochemical transistors based on inkjet printed PEDOT:PSS for biosensing. Book of Abstracts CEITEC Annual Conference “Frontiers in Material and Life Sciences”. První edice. Brno: Masarykova Univerzita, 2014. p. 189-189. ISBN: 978-80-210-7159-9.
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OMASTA, L.; SALYK, O.; HRABAL, M.; WEITER, M. Preparation and optimization of printed layers for biosensing. Chemistry & Life 2015 - Book of Abstracts. first. Brno: Brno University of Technology, Faculty of Chemistry, 2015. p. 140-140. ISBN: 978-80-214-5228-2.
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OMASTA, L.; SALYK, O.; HRABAL, M.; WEITER, M. PRINTED BIOSENSORS BASED ON ORGANIC ELECTROCHEMICAL TRANSISTORS. Book of Abstracts 11th International Conference on Organic Electronics. První. Erlangen-Nurnberg, Nemecko: Friedrich-Alexander Universitat, 2015. p. 58-58.
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Vala, M.; Weiter, M.; Kratochvílová, I.; Páv, O.; Sychrovský, V. Charge transfer in DNA: Influence of molecular structure, flexibility and Hg ion. BioEl2015 International Winterschool on Bioelectronics - Book of abstracts. 2015.
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Weiter, M.; Víteček, J.; Kubala, L.; Šafaříková, E.; Šindelářová, L.; Stříteský, S.; Salyk, O.; Vala, M. Determination of biocompatibility of materials for organic electronic devices. BioEl2015 International Winterschool on Bioelectronics - Book of abstracts. 2015.
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VALA, M.; WEITER, M.; KRAJČOVIČ, J.; LUŇÁK, S.; Kubáč, L. Diketo-pyrrolo-pyrrole: the influence of chemical structure on optical and electrical properties. 12th International Symposium on Functional π-Electron Systems (Fπ-12) - Book of abstracts. 2015.
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STŘÍTESKÝ, S.; WEITER, M.; VALA, M.; HORÁKOVÁ P.; DOKLÁDALOVÁ L.; KUBÁČ L. New Diketopyrrolopyrrole Derivatives in OFET Transistors. Chemistry & Life 2015. BOOK OF ABSTRACT. Brno: 2015. p. 139-139. ISBN: 978-80-214-5228-2.
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STŘÍTESKÝ, S.; WEITER, M.; VALA, M.; ŠIMEK, V.; CRHA, A.; RŮŽIČKA, R. OFET transistors for logical circuit. IFSOE 2015 Book of Abstracts. 2nd International Fall School. Moskva: 2015. p. 99-99.
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VALA, M.; WEITER, M.; KRAJČOVIČ, J. Organic and Printed Photonics – Tailoring of Materials Properties. Wearable technology Europe 2015 - Book of abstracts. 2015.
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VALA, M.; WEITER, M.; KRAJČOVIČ, J. Diketo-pyrrolo-pyrroles: prospective materials for organic photonics. LOPEC 2015 - 7th International Exhibition and Conference for the Printed Electronics Industry - Book of abstracts. 2015.
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KRAJČOVIČ, J.; KOVALENKO, A.; HEINRICHOVÁ, P.; VALA, M.; WEITER, M. Adamantyl side groups boosting the efficiency and thermal stability of organic solid-state fluorescent dyes. Journal of Luminescence, 2016, vol. 2016, no. 175, p. 94-99. ISSN: 0022-2313.
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HRABAL, M.; OMASTA, L.; VALA, M.; WEITER, M. Optimization of Screen Printing Process for Printed Electronic Devices. Chermistry and Life Brno 2015. 2015. p. 138-139. ISBN: 978-80-214-5228-2.
Detail

OMASTA, L.; SALYK, O.; VALA, M.; WEITER, M. Screen printing of organic electrochemical transistor for cardiomyocytes research. In Studentská odborná konference CHemie je život 2015, Sborník abstraktů. Brno: Vysoké učení technické v Brně, Fakulta chemická, Purkyňova 464/118, 612 00 Brno, 2015. p. 375-380. ISBN: 978-80-214-5290-9.
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SALYK, O.; OMASTA, L.; VALA, M.; WEITER, M. Printed Organic Sensor for Cardiomyocytes Research. Chemistry & Life 2015 , Book of Abstracts. first. Brno: Faculty of Chemistry, Brno University of Technology, 2015. p. 147-147. ISBN: 978-80-214-5228-2.
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STŘÍTESKÝ, S.; KRAJČOVIČ, J.; VALA, M.; WEITER, M. The influence of diketopyrrolopyrrole chemical structure on organic field-effect transistors performance. In Materials Science Forum. Materials Science Forum. Applied Chemistry in Solving of Production Goals. Switzerland: © 2016 Trans Tech Publications, 2016. p. 189-193. ISBN: 978-80-214-5228-2. ISSN: 1662-9752.
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SALYK, O.; OMASTA, L.; VALA, M.; WEITER, M. Organic Sensor for Cardiomyocytes Research. Materials Science Forum, 2016, vol. 851, no. 1, p. 194-198. ISSN: 1662-9752.
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Róbert Mišicák, Stanislav Stříteský, Martin Vala, Martin Weiter, Marek Cigán, Katarína Gmucová, Karol Végsö, Martin Weis, Jozef Kožíšek, Milan Pavúk, Martin Putala. Effect of the ethynylene linker on the properties and carrier mobility of naphthalene derivatives with hexylbithienyl arms. Syntetic Metals, 2016, vol. 2016, no. 217, p. 156-171. ISSN: 0379-6779.
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HRABAL, M.; OMASTA, L.; VALA, M.; SALYK, O.; WEITER, M. Printing of thin films for printed electronics. Book of Abstracts of The 12th International Conference on Organic Electronics. Bratislava, Slovakia: Slovak University of Technology in Bratislava, 2016. p. 31-31. ISBN: 978-80-227-4571-0.
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OMASTA, L.; HRABAL, M.; SALYK, O.; VALA, M.; WEITER, M. Printed lateral biosensors based on organic electrochemical transistor. Book of Abstracts of The 12th International Conference on Organic Electronics. Bratislava, Slovakia: Slovak University of Technology in Bratislava, 2016. p. 57-57. ISBN: 978-80-227-4571-0.
Detail

Vala, M.; Koutný, J.; Kovalenko, A.; Krajčovič, J.; Heinrichová, P.; Luňák, S.; Horáková, P.; Kubáč, L.; Vyňuchal, J.; WEITER, M. DIKETOPYRROLOPYRROLES: PERSPECTIVE MATERIALS FOR ORGANIC PHOTONICS. Book of Abstracts of The 12th International Conference on Organic Electronics. Bratislava, Slovakia: Slovak University of Technology in Bratislava, 2016. ISBN: 978-80-227-4571-0.
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Vala, M.; Koutný, J.; Krajčovič, J.; Luňák, S.; WEITER, M. Diketo-pyrrolo-pyrroles: prospective materials for nonlinear optical applications. Gotteborg, Sweeden: Chalmers, 2016.
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Weiter, M.; Víteček, J.; Kubala, L.; Šafaříková, E.; Šindlerová, L.; Stříteský, S.; Salyk, O.; Vala, M. Cardiomyocytes monitoring: Determination of biocompatibility. International Winterschool on Bioelectronics BioEl2015. Linz, Austria: JKU, 2016.
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Vala, M.; Krajčovič, J.; Kovalenko, A.; Yumusak, C.; Heinrichová, P.; Stříteský, S.; Sariciftci, N.S.; Weiter, M. Adamantyl side group containing organic semiconductors for high performance OTFTs. Organic Semiconductors Conference. London, Great Britain: Imperial College London, 2016.
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Vala, M.; Krajčovič, J.; Weiter, M. Diketo-pyrrolo-pyrroles for organic electronics and photonics. International Symposium for the 80th Birthday of Prof. Alan J. Heeger (Nobelprize 2000). Linz, Austria: JKU, 2016.
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SALYK, O.; VÍTEČEK, J.; OMASTA, L.; ŠAFAŘÍKOVÁ, E.; STŘÍTESKÝ, S.; VALA, M.; WEITER, M. Organic Electrochemical Transistor Microplate for Real-Time Cell Culture Monitoring. Applied Sciences - Basel, 2017, vol. 7, no. 10, p. 998-1008. ISSN: 2076-3417.
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ŠAFAŘÍKOVÁ, E.; ŠINDLEROVÁ, L.; STŘÍTESKÝ, S.; KUBALA, L.; VALA, M.; WEITER, M.; VÍTEČEK, J. Evaluation and improvement of organic semiconductors’ biocompatibility towards fibroblasts and cardiomyocytes. Sensors and Actuators B: Chemical, 2017, no. 260, p. 418-425. ISSN: 0925-4005.
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VALA, M.; KRAJČOVIČ, J.; LUŇÁK, S.; OUZZANE, I.; BOUILLON, J-P.; WEITER, M. HOMO and LUMO energy levels of N,N- dinitrophenyl-substituted polar diketopyrrolopyrroles (DPP). DYES AND PIGMENTS, 2014, vol. 2014, no. 106, p. 136-142. ISSN: 0143-7208.
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Odpovědnost: Weiter Martin, prof. Ing., Ph.D.