Detail publikace

Biotransformation of ferulic acid into vanillyl alcohol and vanillic acid employing thermophilic bacterium Caldimonas thermodepolymerans

HRABALOVÁ, V. OPIAL, T. MUSILOVÁ, J. SEDLÁŘ, K. OBRUČA, S.

Originální název

Biotransformation of ferulic acid into vanillyl alcohol and vanillic acid employing thermophilic bacterium Caldimonas thermodepolymerans

Typ

článek v časopise ve Web of Science, Jimp

Jazyk

angličtina

Originální abstrakt

Caldimonas thermodepolymerans , a Gram -negative, moderately thermophilic bacterium, exhibits a remarkable biotechnological potential. Given the presence of genes in its genome dedicated to the metabolization of ferulic acid (FA), this study aimed to explore the bacterium 's capability for biotransforming FA into high -value metabolites. The results unequivocally demonstrate the bacterium 's proficiency in the efficient and rapid conversion of FA into vanillyl alcohol (VOH) and vanillic acid (VA). By manipulating key cultivation parameters, such as adjusting initial FA doses and varying cultivation periods, the product profile can be tailored. Higher initial doses and shorter cultivation periods favor the production of VOH, while lower FA doses and extended cultivation periods lead to the predominant formation of VA. Furthermore, the process can be operated in a repeated-batch scenario. This underscores the potential of C. thermodepolymerans for industrial biotransformation of FA, presenting a promising avenue for leveraging its capabilities in practical applications.

Klíčová slova

Caldimonas thermodepolymerans; Thermophiles; Ferulic acid; Biotransformation; Vanillic acid; Vanillyl alcohol

Autoři

HRABALOVÁ, V.; OPIAL, T.; MUSILOVÁ, J.; SEDLÁŘ, K.; OBRUČA, S.

Vydáno

2. 9. 2024

Nakladatel

ELSEVIER SCIENCE INCSTE 800, 230 PARK AVE, NEW YORK, NY 10169

ISSN

0141-0229

Periodikum

ENZYME AND MICROBIAL TECHNOLOGY

Ročník

179

Číslo

9

Stát

Spojené státy americké

Strany od

1

Strany do

6

Strany počet

6

URL

https://www-sciencedirect-com.ezproxy.lib.vutbr.cz/science/article/pii/S0141022924000826?via%3Dihub

BibTex

@article{BUT189077,
  author="Vendula {Hrabalová} and Tomáš {Opial} and Jana {Musilová} and Karel {Sedlář} and Stanislav {Obruča}",
  title="Biotransformation of ferulic acid into vanillyl alcohol and vanillic acid employing thermophilic bacterium Caldimonas thermodepolymerans",
  journal="ENZYME AND MICROBIAL TECHNOLOGY",
  year="2024",
  volume="179",
  number="9",
  pages="6",
  doi="10.1016/j.enzmictec.2024.110475",
  issn="0141-0229",
  url="https://www-sciencedirect-com.ezproxy.lib.vutbr.cz/science/article/pii/S0141022924000826?via%3Dihub"
}