Detail publikace

Study of cholesterol’s effect on the properties of catanionic vesicular systems

HAVLÍKOVÁ, M. SZABOVÁ, J. CHANG, C. MRAVEC, F.

Originální název

Typ

abstrakt

Jazyk

angličtina

Originální abstrakt

This work is focused on the study of properties and stability catanionic vesicles at laboratory temperature. Catanionic vesicles were based on the ion pair amphiphile (IPA), which was prepared by mixing equivalent volumes of aqueous solution HTMAB (hexadecyltrimethylammonium bromide) and SDS (sodium dodecylsulphate). Then the precipitate was obtained and after removal of the counterions of these surfactants, IPA was formed. The residue IPA was denoted as HTMA-DS. To improve stability positively charged double-chained dioctadecyldimethylammonium chloride (DODAC) and cholesterol were added. The total amount of cholesterol was set to 0, 3, 13, 23, 33, 43, 53, 63 and 73 mol.%. In this system, the size distribution was studied using the dynamic light-scattering (DLS) and zeta potential was determined by electrophoretic light-scattering. These standard techniques were supplemented by fluorescence spectroscopy technique. Specifically, generalized polarization (GP) was measured using a Laurdan probe. This probe is sensitive to fluidity and membrane hydration at a particular temperature.

Klíčová slova

ion pair amphiphile, catanionic vesicles, cholesterol, hydration water, generalized polarization

Autoři

HAVLÍKOVÁ, M.; SZABOVÁ, J.; CHANG, C.; MRAVEC, F.

Vydáno

6. 9. 2021

Strany od

123

Strany do

123

Strany počet

BibTex

@misc{BUT172491,
  author="Martina {Havlíková} and Jana {Szabová} and Chien-Hsiang {Chang} and Filip {Mravec}",
  title="Study of cholesterol’s effect on the properties of catanionic vesicular systems",
  year="2021",
  series="35th Conference of the European Colloid & Interface Society, Book of Abstracts",
  edition="1",
  pages="123--123",
  note="abstract"
}