Detail publikace

Interactions of hyaluronan with oppositely charged surfactants in very diluted solutions in water

PILGROVÁ, T. VENEROVÁ, T. MRAVEC, F. PEKAŘ, M.

Originální název

Interactions of hyaluronan with oppositely charged surfactants in very diluted solutions in water

Typ

článek v časopise ve Web of Science, Jimp

Jazyk

angličtina

Originální abstrakt

The phase behavior of aqueous systems containing hyaluronan, at concentrations between 2 to 100 mg/L, and oppositely charged surfactants was investigated. A fluorescence probe technique revealed the formation of micellar structures on the hyaluronan in homogeneous systems well below the surfactant standard, critical, micellar concentration. Moreover, regions of gel-phase separation were revealed. A detailed phase diagram was, thus, constructed in the very diluted region and the hyaluronan concentration was found to be the main parameter controlling the phase behavior, in contrast to the charge ratio. The stability of hyaluronan-surfactant aggregates in the homogeneous systems while in storage at 4 °C (up to three months), against dilution, salt addition and on heating-cooling (between 10 and 50 °C) was also investigated. The aggregates were stable while in storage or upon increasing and decreasing the temperature. The dilution of hyaluronan-surfactant complexes or the addition of 0.15 M NaCl led to their disintegration. Finally, systems prepared in a 0.15 M NaCl solution showed that interactions are suppressed and no aggregation below the standard critical micellar concentration was observed.

Klíčová slova

hyaluronan; interactions; surfactants

Autoři

PILGROVÁ, T.; VENEROVÁ, T.; MRAVEC, F.; PEKAŘ, M.

Vydáno

1. 2. 2018

ISSN

0141-8130

Periodikum

INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES

Ročník

112

Číslo

1

Stát

Nizozemsko

Strany od

241

Strany do

249

Strany počet

9

URL

https://doi.org/10.1016/j.ijbiomac.2018.01.176

BibTex

@article{BUT145670,
  author="Tereza {Pilgrová} and Tereza {Venerová} and Filip {Mravec} and Miloslav {Pekař}",
  title="Interactions of hyaluronan with oppositely charged surfactants in very
diluted solutions in water",
  journal="INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES",
  year="2018",
  volume="112",
  number="1",
  pages="241--249",
  doi="10.1016/j.ijbiomac.2018.01.176",
  issn="0141-8130",
  url="https://doi.org/10.1016/j.ijbiomac.2018.01.176"
}