Detail publikace

Antibacterial activity and cell viability of hyaluronan fiber with silver nanoparticles

ABDEL-MOHSEN, A.M. HRDINA, R. BURGERT, L. ABDEL-RAHMAN, R. M. HAŠOVÁ, M. ŠMEJKALOVÁ, D. KOLÁŘ, M. PEKAŘ, M. ALY, A.S.

Originální název

Antibacterial activity and cell viability of hyaluronan fiber with silver nanoparticles

Typ

článek v časopise - ostatní, Jost

Jazyk

angličtina

Originální abstrakt

Silver has been used since time immemorial in different chemical form to treat burns, wounds and several different infections caused by pathogenic bacteria, advancement of biological process of nanoparticles synthesis is evolving into a key area of nanotechnology. The current study deals with the green synthesis, characterization, and evaluation of the biological activity and cell viability of hyaluronan fibers with incorporated silver nanoparticles (HA-Ag NPs). Hyaluronan fiber was prepared by the dissolving of sodium hyaluronate (HA) in aqueous alkaline solution to prepare a transparent solution, which was used for the preparation of fibers by a wet-spinning technique. Consequently, hyaluronan fiber was used as capping and stabilizing agent for the preparation of fibers with silver nanoparticles. HA-Ag NPs were confirmed by transmission electron microscopy, dynamic light scattering, UV/VIS spectroscopy, scanning electron microscopy, energy-dispersive X-ray spectroscopy, thermal analysis, nuclear magnetic resonance, Fourier transform infrared spectroscopy, and X-ray photoelectron spectroscopy. HA-Ag NPs showed high antibacterial activity of against Staphylococcus aureus and Escherichia coli. Cell viability tests indicated that hyaluronan, hyaluronan fibers and hyaluronan fibers with silver nanoparticles were non-toxic on the cell growth. Two different particles size of Ag NPs (10, 40 nm) had not any toxicity till the concentration limit. These tests were performed using mouse fibroblast cell line 3T3.

Klíčová slova

Green chemistry, Hyaluronan fiber, Silver nanoparticles, Cell viability, Antibacterial activity, Medical applications

Autoři

ABDEL-MOHSEN, A.M.; HRDINA, R.; BURGERT, L.; ABDEL-RAHMAN, R. M.; HAŠOVÁ, M.; ŠMEJKALOVÁ, D.; KOLÁŘ, M.; PEKAŘ, M.; ALY, A.S.

Rok RIV

2012

Vydáno

1. 11. 2012

ISSN

0144-8617

Periodikum

Carbohydrate Polymers

Ročník

92

Číslo

2

Stát

Spojené království Velké Británie a Severního Irska

Strany od

1177

Strany do

1187

Strany počet

11

BibTex

@article{BUT98008,
  author="ABDEL-MOHSEN, A.M. and HRDINA, R. and BURGERT, L. and ABDEL-RAHMAN, R. M. and HAŠOVÁ, M. and ŠMEJKALOVÁ, D. and KOLÁŘ, M. and PEKAŘ, M. and ALY, A.S.",
  title="Antibacterial activity and cell viability of hyaluronan fiber with silver nanoparticles",
  journal="Carbohydrate Polymers",
  year="2012",
  volume="92",
  number="2",
  pages="1177--1187",
  issn="0144-8617"
}