Detail publikace

The assessment of contamination of selected river streams in the Czech Republic by human and veterinary drug residues with liquid and gas chromatography

LACINA, P. DVOŘÁKOVÁ, P. VÁVROVÁ, M.

Originální název

Typ

článek v časopise - ostatní, Jost

Jazyk

angličtina

Originální abstrakt

This study monitors presence of selected drug residues in two rivers in the Czech Republic. High performance liquid chromatography with mass spectrometric detection (HPLC-MS) and comprehensive two-dimensional gas chromatography with mass spectrometric detection Time-of-Flight (GCxGC-TOF MS) are applied for determination of selected drug residues. HPLC-MS was used for determination of drugs from the group of sulfonamide antibiotics and GCxGC-TOF MS was used for determination of drugs from the group of non-steroidal anti-inflammatory drugs. Presence of selected contaminants was monitored in two rivers (the river Svratka and the river Svitava) in Moravia region in the Czech Republic. Samples were collected along the river streams in March 2011. Solid phase extraction (SPE) method was used for extraction and preconcentration of analytes. Limits of detection were ranged from 0.24 to 2.55 ug.L-1 for sulfonamides analysed by HPLC-MS and from 0.18 to 5 ng.L-1 for non-steroidal anti-inflammatory drugs analysed by GCxGC-TOF MS; both ranges depending on specific compound. On some sampling places were found following drugs: sulfapyridine, sulfamerazine, sulfamethazine, sulfamethoxazole with concentrations in units of ug.L-1 and salicylic acid, ibuprofen, caffeine, naproxen, ketoprofen and diclofenac with range of concentrations from units to hundreds of ng.L-1.

Klíčová slova

drug residues; non-steroidal anti-inflammatory drugs; sulfonamide antibiotics; liquid chromatography; gas chromatography; surface water

Autoři

LACINA, P.; DVOŘÁKOVÁ, P.; VÁVROVÁ, M.

Rok RIV

2012

Vydáno

1. 11. 2012

ISSN

1018-4619

Periodikum

Fresenius Environmental Bulletin

Ročník

Číslo

11a

Stát

Spolková republika Německo

Strany od

3318

Strany do

3324

Strany počet

BibTex

@article{BUT95507,
  author="Petr {Lacina} and Petra {Dvořáková} and Milada {Vávrová}",
  title="The assessment of contamination of selected river streams in the Czech Republic by human and veterinary drug residues with liquid and gas chromatography",
  journal="Fresenius Environmental Bulletin",
  year="2012",
  volume="21",
  number="11a",
  pages="3318--3324",
  issn="1018-4619"
}