Detail publikace

Comparison of Negative-ion Electrospray Mass Spectra Measured by Seven Tandem Mass Analyzers Towards Library Formation

VOLNÁ, K. HOLČAPEK, M. KOLÁŘOVÁ, L. LEMR, K. ČÁSLAVSKÝ, J. KAČER, P. POUSTKA, J. HUBÁLEK, M.

Originální název

Typ

článek v časopise - ostatní, Jost

Jazyk

angličtina

Originální abstrakt

A library of negative ion electrospray ionization mass spectra and tandem mass spectra (MS/MS) of sulfonated dyes has been developed for fast identification purposes. The uniform protocol has been elaborated and applied to the measurements of more than 50 anionic dyes. Three collision energies are selected in our protocol which ensures that at least one of them provides a suitable ratio of product ions to the precursor ion. The robustness is investigated with altered values of tuning parameters (e.g. the pressure of the nebulizing gas, the temperature and the flow rate of drying gas, and the mobile phase composition). The results of the inter-laboratory comparison of product ion mass spectra recorded on seven different tandem mass spectrometers (three ion traps, two triple quadrupoles and two hybrid quadrupole time of flight instruments) are presented for four representative anionic dyes - azo dye Acid Red 118, anthraquinone dye Acid Violet 43, triphenylmethane dye Acid Blue 1 and Al(III) metal-complex azo dye. The fragmentation patterns are almost identical for all tandem mass analyzers, only the ratios of product ions differ somewhat which confirms the possibility of spectra transfer among different mass analyzers with the goal of library formation.

Klíčová slova

chromatography/mass spectrometry instruments; collisionally induced dissociation; liquid-chromatography; sulfonated dyes; azo dyestuffs; ionization; drugs; trap; identification; searching

Autoři

VOLNÁ, K.; HOLČAPEK, M.; KOLÁŘOVÁ, L.; LEMR, K.; ČÁSLAVSKÝ, J.; KAČER, P.; POUSTKA, J.; HUBÁLEK, M.

Rok RIV

2008

Vydáno

30. 1. 2008

Nakladatel

Wiley

Místo

London

ISSN

0951-4198

Periodikum

RAPID COMMUNICATIONS IN MASS SPECTROMETRY

Ročník

Číslo

Stát

Spojené království Velké Británie a Severního Irska

Strany od

101

Strany do

108

Strany počet

BibTex

@article{BUT43497,
  author="Kateřina {Volná} and Michal {Holčapek} and Karel {Lemr} and Josef {Čáslavský} and Petr {Kačer} and Jan {Poustka}",
  title="Comparison of Negative-ion Electrospray Mass Spectra Measured by Seven Tandem Mass Analyzers Towards Library Formation",
  journal="RAPID COMMUNICATIONS IN MASS SPECTROMETRY",
  year="2008",
  volume="22",
  number="2",
  pages="101--108",
  issn="0951-4198"
}