CHARACTERIZATION OF BIOLOGICAL EFFECTS OF EXTRACTS OBTAINED FROM YEASTS

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Carotenogenic yeasts belong to the class Basidiomycota, which includes the following yeast genera: Cystofilobasidium, Rhodotorula and Sporobolomyces. All these genera are characterized by overproduction of carotenoids. If these genera have ideal conditions, they also produce high amounts of lipids. In addition, these lipids consist of fatty acids characterized by a high content of polyunsaturated and monounsaturated fatty acids, which find a wide range of uses in the food, pharmaceutical and agricultural industries. Therefore, carotenogenic yeasts are increasingly being investigated in the biotechnological industry [1-4]. The goal was to find out how carotenogenic yeast will behave in the presence of stress factors, and which of these stresses will have a positive effect on the production of metabolites that can be further used in various industries. The experimental part dealt with the exposure of carotenogenic yeasts to oxidative stress and stress induced by heavy metals. The goal was to find out which concentrations of these stress factors are lethal for microorganisms, and which are optimal for increasing the production of the above-mentioned substances. Of the yeast strains, Sporidiobolus pararoseus and Rhodotorula mucilaginosa strains achieved increased production of metabolites under the influence of selenate ions. Conversely, cobalt showed a favorable effect only on the accumulation of lipids in cells and β-glucans. However, the highest changes in metabolite production were achieved by addition of the optimal concentration of the oxidative stress-inducing solution.

30. 11. 2022

Vysoké učení technické v Brně, Fakulta chemická,Purkyňova 464/118, 612 00 Brno

Brno

978-80-214-6117-8

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první

32

32

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