Detail publikace

Adsorption/desorption behavior of hyaluronic acid fragments at charged hydrophobic surface

ŠVECOVÁ, E. OSTATNÁ, V. FOJT, L. HERMANNOVÁ, M. VELEBNÝ, V. ONDREÁŠ, F.

Originální název

Adsorption/desorption behavior of hyaluronic acid fragments at charged hydrophobic surface

Typ

článek v časopise ve Web of Science, Jimp

Jazyk

angličtina

Originální abstrakt

This work reveals the growing potential of novel electrochemical methods that are applicable for polysaccharides. It was shown for the first time that the molecules of hyaluronic acid (HA) exhibit electrochemical response using phase-sensitive alternating current (AC) voltammetry in phase-out mode. Adsorption and desorption processes of HA fragments at a charged interface of mercury electrode were observed in buffered HA solutions. Electrostatic and hydrophobic manners of interactions were distinguished for native hyaluronan fragments in a wide electric potential range. The AC voltammetry response depended on the temperature, concentration, and length of HA chains. Results of this work open possibilities for further structural characterization of widely used HA fragments and understanding manners of interactions with charged hydrophobic surfaces that could be useful in the future for understanding HA interactions at biological levels.

Klíčová slova

Alternating current voltammetry; Hyaluronic acid; Adsorption and desorption; Differential capacitance of the electrical double layer; Hanging mercury drop electrode

Autoři

ŠVECOVÁ, E.; OSTATNÁ, V.; FOJT, L.; HERMANNOVÁ, M.; VELEBNÝ, V.; ONDREÁŠ, F.

Vydáno

1. 2. 2022

Nakladatel

ELSEVIER SCI LTD

Místo

OXFORD

ISSN

1879-1344

Periodikum

Carbohydrate Polymers (electronic)

Ročník

277

Číslo

118831

Stát

Spojené království Velké Británie a Severního Irska

Strany počet

8

URL

https://www.sciencedirect.com/science/article/pii/S0144861721012182?via%3Dihub

BibTex

@article{BUT182247,
  author="Eliška {Švecová} and Veronika {Ostatná} and Lukáš {Fojt} and Martina {Hermannová} and Vladimír {Velebný} and František {Ondreáš}",
  title="Adsorption/desorption behavior of hyaluronic acid fragments at charged hydrophobic surface",
  journal="Carbohydrate Polymers (electronic)",
  year="2022",
  volume="277",
  number="118831",
  pages="8",
  doi="10.1016/j.carbpol.2021.118831",
  issn="1879-1344",
  url="https://www.sciencedirect.com/science/article/pii/S0144861721012182?via%3Dihub"
}