Structural and Transport Properties of Hybrid Hydrogel Based on Sodium Alginate and Polyvinyl Alcohol

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This work is focused on the preparation and subsequent characterization of structural and transport properties of hybrid hydrogels with the double-network structure concerning their application potencial. With regard to already existing research papers, hybrid hydrogels were prepared as a combination of synthetic polymer and natural polysaccharide, such as polyvinyl alcohol and sodium alginate. In the preparation of this gel's hybrid network involved physical cross-linking of PVA by the freeze-thaw method, and ionic cross-linking of sodium alginate by calcium ions. Another part of this work is tailoring of the internal strucutre of hybrid hydrogels with lecithin as a model of the phospholipid bilayer forming the cell membrane or occurring in tissue. Physicochemical methods were used to characterize their visocelastic, swelling and transport properties. Rheology measurements, specifically oscillation and amplitude tests, were used to study these viscoelastic properties. Morphology of the prepared hybrid hydrogels were confirmed by electron mecroscope scanning. Transport and release properties of gel systems were determined by diffusion experiments with the UV-VIS spectrometry detection, in which an organic dye (methylene blue) was used as a model probe.

Hybrid network, hydrogel, lecithin, rheology, swelling, SEM, diffusion experiments, internal strucutre

ZHURAULIOVA, D.; SMILEK, J.; PEKAŘ, M.

30. 11. 2022

Vysoké učení technické v Brně, Fakulta chemická

Brno, CZ

978-80-214-6117-8

Studentská odborná konference Chemie je život 2022 Sborník abstraktů

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